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Bigger AI chatbots more inclined to spew nonsense — and people don't always realize

mercredi 25 septembre 2024 par Nicola Jones

Nature, Published online: 25 September 2024; doi:10.1038/d41586-024-03137-3Artificial-intelligence models are improving overall but are more likely to answer every question, leading to wrong answers.

Nature

How a ‘billion oysters’ could protect the New York coastline from climate change

mercredi 25 septembre 2024 par Alix Soliman

Nature, Published online: 25 September 2024; doi:10.1038/d41586-024-03118-6Advocates argue that restoring the oyster reefs that once armoured shorelines could help to buffer against extreme storms.

Nature

How pain is misunderstood and ignored in women

mercredi 25 septembre 2024 par Bianca Nogrady

Nature, Published online: 25 September 2024; doi:10.1038/d41586-024-03005-0Sex hormones seem to have profound effects, but research mostly avoids the question of sex.

Nature

A drug-free prescription for pain

mercredi 25 septembre 2024 par Carolyn Brown

Nature, Published online: 25 September 2024; doi:10.1038/d41586-024-03007-yNon-invasive, non-pharmacological approaches such as virtual-reality therapy and yoga can help to relieve chronic pain.

Nature

Using both faces of polar semiconductor wafers for functional devices

mercredi 25 septembre 2024 par Len van Deurzen, Eungkyun Kim, Naomi Pieczulewski, Zexuan Zhang, Anna Feduniewicz-Zmuda, Mikolaj Chlipala, Marcin Siekacz, David Muller, Huili Grace Xing, Debdeep Jena, Henryk Turski

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07983-zA new approach is described for fabricating devices on each of the faces of the same gallium nitride semiconductor wafer, using the cation face for photonic devices and the anion face for electronic (...)

Nature

Bendable non-silicon RISC-V microprocessor

mercredi 25 septembre 2024 par Emre Ozer, Jedrzej Kufel, Shvetank Prakash, Alireza Raisiardali, Olof Kindgren, Ronald Wong, Nelson Ng, Damien Jausseran, Feras Alkhalil, David Kong, Gage Hills, Richard Price, Vijay Janapa Reddi

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07976-yFlex-RV, a 32-bit microprocessor based on an open RISC-V instruction set fabricated with indium gallium zinc oxide thin-film transistors on a flexible polyimide substrate, enables an ultralow-cost bendable and flexible (...)

Nature

Designed endocytosis-inducing proteins degrade targets and amplify signals

mercredi 25 septembre 2024 par Buwei Huang, Mohamad Abedi, Green Ahn, Brian Coventry, Isaac Sappington, Cong Tang, Rong Wang, Thomas Schlichthaerle, Jason Z. Zhang, Yujia Wang, Inna Goreshnik, Ching Wen Chiu, Adam Chazin-Gray, Sidney Chan, Stacey Gerben, Analisa Murray, Shunzhi Wang, Jason O’Neill, Li Yi, Ronald Yeh, Ayesha Misquith, Anitra Wolf, Luke M. Tomasovic, Dan I. Piraner, Maria J. Duran Gonzalez, Nathaniel R. Bennett, Preetham Venkatesh, Maggie Ahlrichs, Craig Dobbins, Wei Yang, Xinru Wang, Danny D. Sahtoe, Dionne Vafeados, Rubul Mout, Shirin Shivaei, Longxing Cao, Lauren Carter, Lance Stewart, Jamie B. Spangler, Kole T. Roybal, Per Jr Greisen, Xiaochun Li, Gonçalo J. L. Bernardes, Carolyn R. Bertozzi, David Baker

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07948-2Computationally designed genetically encoded proteins can be used to target surface proteins, thereby triggering endocytosis and subsequent intracellular degradation, activating signalling or increasing cellular uptake (...)

Nature

Brazilian fossils reveal homoplasy in the oldest mammalian jaw joint

mercredi 25 septembre 2024 par James R. G. Rawson, Agustín G. Martinelli, Pamela G. Gill, Marina B. Soares, Cesar L. Schultz, Emily J. Rayfield

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07971-3The dentary–squamosal contact, traditionally considered to be a typical mammalian feature, evolved more than once and is more evolutionary labile than previously (...)

Nature

Microbial iron limitation in the ocean’s twilight zone

mercredi 25 septembre 2024 par Jingxuan Li, Lydia Babcock-Adams, Rene M. Boiteau, Matthew R. McIlvin, Lauren E. Manck, Matthias Sieber, Nathan T. Lanning, Randelle M. Bundy, Xiaopeng Bian, Iulia-M?d?lina ?treang?, Benjamin N. Granzow, Matthew J. Church, Jessica N. Fitzsimmons, Seth G. John, Tim M. Conway, Daniel J. Repeta

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07905-zThe distribution and uptake of siderophores across a meridional section of the eastern Pacific Ocean suggests that iron availability limits microbial metabolism in the upper mesopelagic in several large ocean (...)

Nature

AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases

mercredi 25 septembre 2024 par Heyu Li, Chao Liu, Ran Li, Lili Zhou, Yu Ran, Qiqing Yang, Huizhe Huang, Huasong Lu, Hai Song, Bing Yang, Heng Ru, Shixian Lin, Long Zhang

Nature, Published online: 25 September 2024; doi:10.1038/s41586-024-07992-yThe tRNA synthases AARS1 and AARS2 are identified as evolutionarily conserved sensors of intracellular l-lactate to mediate the global lysine lactylome.

Nature