Sur le Web

Nouveautés sur le Web

Articles les plus récents

Two decades of PARP inhibitor synthetic lethality in cancer

mercredi 6 mai 2026 par Christopher J. Lord, Andrew N. J. Tutt, Alan Ashworth

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10404-yThe past two decades of PARP inhibitor synthetic lethality in cancer is explored.

Nature

Systematic partisan content skews in TikTok during the 2024 US elections

mercredi 6 mai 2026 par Hazem Ibrahim, HyunSeok Daniel Jang, Nouar Aldahoul, Aaron R. Kaufman, Talal Rahwan, Yasir Zaki

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10447-1Audit experiments on TikTok show asymmetric partisan exposure that is not explained by observable engagement metrics, with Republican-leaning accounts receiving more aligned content and Democratic-leaning accounts more (...)

Nature

Androgen loss accelerates brain tumour growth via HPA axis activation

mercredi 6 mai 2026 par Juyeun Lee, Yoon-Mi Chung, Daniel J. Silver, Yue Hao, Dylan Scott Lykke Harwood, Alyssa Ealy, Amanda M. Serapiglia, Lee Curtin, Julia R. Benedetti, Christine Ann Pittman Ballard, Kamya Lapsley, Andrea Alvarez-Vazquez, Jessica Goldberg, Cathy Li, Sehaj Kaur, Rian Neal, Sabrina Z. Wang, Kristen E. Kay, Josephine Volovetz, Ellen S. Hong, R’ay Fodor, Jakub Jarmula, Michael Nicosia, Joshua B. Rubin, Kristin R. Swanson, Quinn T. Ostrom, Nikhil Panicker, Bjarne Winther Kristensen, Michael Berens, Nima Sharifi, Justin D. Lathia

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10451-5Androgens have distinct roles in the brain, acting as immune-based tumour suppressors through neuroinflammation and neuroendocrine mechanisms.

Nature

Extreme galaxy-scale outflows are frequent among luminous early quasars

mercredi 6 mai 2026 par Weizhe Liu, Xiaohui Fan, Huan Li, Richard Green, Jinyi Yang, Xiangyu Jin, Jianwei Lyu, Maria Pudoka, Yongda Zhu, Eduardo Bañados, Silvia Belladitta, Thomas Connor, Tiago Costa, Roberto Decarli, Anna-Christina Eilers, Hyunsung D. Jun, Madeline A. Marshall, Chiara Mazzucchelli, Jan-Torge Schindler, Yue Shen, Sylvain Veilleux, Julien Wolf, Huanian Zhang, Mingyang Zhuang, Siwei Zou, Mingyu Li

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10477-9James Webb Space Telescope observations show powerful high-redshift quasar outflows, supporting quasar feedback as a key mechanism driving rapid star-formation quenching in early massive (...)

Nature

A brain reward circuit inhibited by next-generation weight-loss drugs in mice

mercredi 6 mai 2026 par Elizabeth N. Godschall, Taha Bugra Gungul, Isabelle R. Sajonia, Aleyna K. Buyukaksakal, Orien Li, Sophia Ogilvie, Austin B. Keeler, Guilian Tian, Yu Shi, Omar Koita, Chloe Xinzhu Guo, Tyler C. J. Deutsch, Eric J. Steacy, Maisie Crook, YuChen Zhang, Nicholas J. Conley, Gulsun Memi, Addison N. Webster, O. Yipkin Calhan, Weile Liu, Amani Akkoub, Karan Malik, Kaleigh I. West, Sara Michel-Le, Arun Karthikeyan, Grace van Gerven, Olivia A. Dell’Aglio, Kevin T. Beier, Larry S. Zweifel, Manoj K. Patel, John N. Campbell, Christopher D. Deppmann, Ali D. Güler

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10444-4Humanized glucagon-like peptide 1 receptor (GLP1R) mouse models are used to investigate the neural circuitry through which small-molecule GLP1R agonists modulate feeding, with implications for how these orally delivered (...)

Nature

Deforestation-induced drying lowers Amazon climate threshold

mercredi 6 mai 2026 par Nico Wunderling, Boris Sakschewski, Johan Rockström, Bernardo M. Flores, Marina Hirota, Arie Staal

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10456-0The Amazon forest faces a near system-wide transition of 62−77% of the area under a combination of 1.5–1.9 °C global warming and 22−28% deforestation.

Nature

Molecular skeleton programming of premediators in sulfur electrochemistry

mercredi 6 mai 2026 par Runhua Gao, Yifei Zhu, Shengyu Tao, Mengtian Zhang, Zhoujie Lao, Zhiyuan Han, Yanze Song, Hongtai Li, Linxuan Song, Xuan Zhang, Yanfei Zhu, Guangmin Zhou

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10505-8A potential premediator, 2-chloropyrimidine, could be a model material for molecular skeleton design enabling lithium–sulfur batteries to achieve a strong average capacity retention and help design functional molecules in (...)

Nature

Imaging the flat bands of magic-angle graphene reshaped by interactions

mercredi 6 mai 2026 par J. Xiao, A. Inbar, J. Birkbeck, N. Gershon, Y. Zamir, Y. Vituri, T. Taniguchi, K. Watanabe, E. Berg, S. Ilani

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10378-xQuantum twisting microscopy is used to directly image the interacting energy bands of magic-angle twisted bilayer graphene, allowing characterization of the dual nature of its electrons at the magic (...)

Nature

Quantum coherent manipulation and readout of superconducting vortex states

mercredi 6 mai 2026 par Ameya Nambisan, Simon Günzler, Dennis Rieger, Nicolas Gosling, Simon Geisert, Victor Carpentier, Nicolas Zapata, Mitchell Field, Milorad V. Miloševi?, Carlos A. Diaz Lopez, Ciprian Padurariu, Björn Kubala, Joachim Ankerhold, Wolfgang Wernsdorfer, Martin Spiecker, Ioan M. Pop

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10441-7Vortices trapped in superconducting granular aluminium films can behave as a quantum two-level system that can be manipulated and read out, suggesting that they could be used for future quantum (...)

Nature

HIV-1 signalling remodels nuclear pores to licence infection

mercredi 6 mai 2026 par Dejan Mesner, Matthew V. X. Whelan, Maitreyi Shivkumar, Ann-Kathrin Reuschl, Riccardo Zenezini Chiozzi, Konstantinos Thalassinos, Robertus A. M. de Bruin, Clare Jolly

Nature, Published online: 06 May 2026; doi:10.1038/s41586-026-10453-3HIV-1 capsid nuclear import at the nuclear pore complex is a bottleneck to resting T cell infection, but HIV-1 overcomes this by triggering receptor-mediated signalling during cell–cell spread to drive nuclear import and (...)

Nature