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These ‘master’ proteins protect us from deadly mutations — and could inspire new drugs

mercredi 17 juin 2026 par Philip Ball

Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01883-0Biology has clever ways to mask the effects of potentially harmful gene mutations. Scientists are investigating how this ‘buffering’ works — and how to exploit (...)

Nature

Probing picometre-scale interlayer deformations via hyperbolic polaritons

mercredi 17 juin 2026 par Shu Zhang, Xiangdong Guo, Xiaowen Zhang, Jiashu Yang, Qinzheng Yu, Zhengyang Mou, Bingze Wu, Chenchen Wu, Shiyu Yang, Yongxin Lan, Peiyi He, Jing Shi, Kaijun Feng, Yuxiang Gao, Qiang Zheng, Shuang Zhang, F. Javier García de Abajo, Zhipei Sun, Mingguang Yao, Feng Ding, Peng Gao, Xiaoxia Yang, Qing Dai

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10638-wA new polaritonic optical method that uses the mid-infrared out-of-plane hyperbolic polaritons mode is described and experimentally validated to allow the examination of picometre-scale interlayer deformations, providing a (...)

Nature

Optical fibre gripper for high-performance 3D micromanipulation

mercredi 17 juin 2026 par Deng Pan, Kaiwen Liang, Chen Xin, Lei Zhong, Shaojun Jiang, Chenchu Zhang, Liang Yang, Zhiqiang Wang, Zhaoxin Lao, Jincheng Ni, Chaowei Wang, Jiawen Li, Shenglai Zhen, Benli Yu, Zhixiang Huang, Fang-Wen Sun, Jiaru Chu, Yanlei Hu, Li Zhang, Dong Wu

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10673-7A miniature three-dimensional optical fibre gripper enables powerful, precise micromanipulation of particles and single cells in confined spaces, bridging the gap between optical and mechanical (...)

Nature

A prototype differential atom interferometer for fundamental physics

mercredi 17 juin 2026 par C. F. A. Baynham, R. Hobson, O. Buchmüller, D. Evans, L. Hawkins, L. Iannizzotto Venezze, A. Josset, D. Lee, E. Pasatembou, B. E. Sauer, M. R. Tarbutt, T. Walker, O. Ennis, U. Chauhan, A. Brzakalik, S. Dey, S. Hedges, B. Stray, M. Langlois, K. Bongs, T. Hird, S. Lellouch, M. Holynski, B. Bostwick, J. Chen, Z. Eyler, V. Gibson, T. L. Harte, C. C. Hsu, M. Karzazi, C. Lu, B. Millward, J. Mitchell, N. Mouelle, B. Panchumarthi, J. Scheper, U. Schneider, X. Su, Y. Tang, K. Tkal?ec, M. Zeuner, S. Zhang, Y. Zhi, L. Badurina, A. Beniwal, D. Blas, J. Carlton, J. Ellis, C. McCabe, G. Parish, D. Pathak Govardhan, V. Vaskonen, T. Bowcock, K. Bridges, A. Carroll, J. Coleman, G. Elertas, S. Hindley, C. Metelko, H. Throssell, J. N. Tinsley, E. Bentine, M. Booth, D. Bortoletto, N. Callaghan, C. Foot, C. Gómez-Monedero, K. Hughes, A. James, T. Leese, A. Lowe, J. March-Russell, J. Sander, J. Schelfhout, I. Shipsey, D. Weatherill, D. Wood, S. N. Balashov, M. G. Bason, K. Hussain, H. Labiad, P. Majewski, A. L. Marchant, D. Newbold, Z. Pan, Z. Tam, T. C. Thornton, T. Valenzuela, M. G. D. van der Grinten, I. Wilmut, K. Clarke, A. Vick

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10617-1A prototype differential atom interferometer operates at the standard quantum limit with no excess noise beyond atom shot noise, achieving performance in line with the specifications for future long-baseline atom (...)

Nature

Structure of the pre-initiation complex explains CMGE biogenesis

mercredi 17 juin 2026 par Thomas Pühringer, Berta Canal, Giacomo Palm, Agata Butryn, Emma C. Couves, Oliver Willhoft, Jacob S. Lewis, John F. X. Diffley, Alessandro Costa

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10657-7Cryo-electron microscopy and biochemical reconstitution experiments in yeast provide insight into the assembly of the CMGE complex, a helicase that establishes bidirectional DNA replication in eukaryotic cells, and elucidate (...)

Nature

A distant brown dwarf coplanar to a warm Jupiter and a hot super-Earth

mercredi 17 juin 2026 par Matías I. Jones, Luca Naponiello, Trifon Trifonov, Rafael Brahm, Gabriele Pichierri, Lorena Acuña-Aguirre, Robert J. De Rosa, Marcelo Tala Pinto, Aldo S. Bonomo, Luigi Mancini, Alessandro Sozzetti, Yared Reinarz, Alessandro Morbidelli, Néstor Espinoza, Giovanni Rosotti, Eric L. Nielsen, Stefan Y. Stefanov, Thomas Henning, Andrés Jordán, Jan Eberhardt, Artie Hatzes, Leonardo Vanzi, Jan Janik, Petr Kabath

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10586-5Analysis of long-term radial velocity data and transit time variations, induced by a super-Earth, a warm Jupiter and a brown dwarf in a coplanar orbit around the relatively young star (...)

Nature

Emergent decadal predictability in Antarctic contribution to sea-level rise

mercredi 17 juin 2026 par Felicity S. McCormack, Mathieu Morlighem, Frank Pattyn, Alexander A. Robel, Hélène Seroussi

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10614-4Although Antarctic ice loss projections diverge widely by 2100, this Perspective shows that present-day rates robustly predict mid-century sea level rise, providing a firm basis for near-term planning, while highlighting (...)

Nature

DNA from hunter-gatherer teeth reveals secrets of ancient plague

mercredi 17 juin 2026 par Benjamin Thompson, Nick Petri? Howe

Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01941-7Analysis shows evidence of deadly outbreaks 5,500 years ago — plus, a prototype dark-matter detector.

Nature

Fiery data hint that controlled forest fires benefit human health

mercredi 17 juin 2026

Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01868-zAnalysis of wildfire in California suggests a net reduction in exposure to blaze-related air pollution.

Nature

The brain region that could provide a cognitive ‘reservoir’ in old age

mercredi 17 juin 2026

Nature, Published online: 17 June 2026; doi:10.1038/d41586-026-01870-5Having a greater tissue volume in some parts of the cerebellum is linked to higher scores on cognitive tests.

Nature