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Daily briefing: Around seven hours of sleep slows biological ageing

jeudi 14 mai 2026 par Jacob Smith

Nature, Published online: 14 May 2026; doi:10.1038/d41586-026-01578-6Between six and eight hours of sleep each day seems to be a ‘sweet spot’ for preventing disease. Plus, unexpected interbreeding between Denisovans and Homo erectus, and how the look of antibiotics could be driving antimicrobial (...)

Nature

Large-scale discovery, analysis and design of protein energy landscapes

mercredi 13 mai 2026 par Állan J. R. Ferrari, Sugyan M. Dixit, Jane Thibeault, Mario Garcia, Scott Houliston, Robert W. Ludwig, Pascal Notin, Claire M. Phoumyvong, Cydney M. Martell, Michelle D. Jung, Kotaro Tsuboyama, Lauren Carter, Cheryl H. Arrowsmith, Miklos Guttman, Gabriel J. Rocklin

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10465-zAn analysis of 5,778 domains 28–64 amino acids in length reveals hidden variation in conformational fluctuations, even between sequences sharing the same fold and global folding (...)

Nature

Subspace communication in the hippocampal–retrosplenial axis

mercredi 13 mai 2026 par Joaquin Gonzalez, Mihály Vöröslakos, Deren Aykan, Nina Soto, Noam Nitzan, Rachel Swanson, Mursel Karadas, Zhe Sage Chen, György Buzsáki

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10481-zHippocampal–neocortical communication reconfigures predetermined circuit motifs to flexibly encode experiences.

Nature

Adaptive cellular evolution in the intestine of hyperdiverse cichlid fishes

mercredi 13 mai 2026 par Antoine Fages, Maëva Luxey, Fabrizia Ronco, Charlotte E. T. Huyghe, Sabrina Fischer, Gudrun Viktorin, P. Navaneeth Krishna Menon, Adrian Indermaur, Walter Salzburger, Patrick Tschopp

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10494-8Single-cell transcriptomics combined with morphological and ecological data show that the rapid evolutionary radiation of cichlid fishes in Lake Tanganyika was accompanied by dietary specialization across multiple layers of (...)

Nature

Mesoscale atomic engineering in a crystal lattice

mercredi 13 mai 2026 par Julian Klein, Kevin M. Roccapriore, Mads Weile, Sergii Grytsiuk, Andrew R. Lupini, Zdenek Sofer, Dimitar Pashov, Mark van Schilfgaarde, Swagata Acharya, Malte Rösner, Frances M. Ross

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10431-9Electron-beam control enables deterministic placement of tens of thousands of atomic defects in three-dimensional crystals, creating stable, programmable artificial matter for scalable quantum and nanoscale (...)

Nature

Lineage and organ signals sequentially build organ intrinsic nervous systems

mercredi 13 mai 2026 par I-Uen Yvonne Hsu, Jia Zhao, Yingxin Lin, Yunshan Guo, Qian J. Xu, Yuancheng Shao, Ruiqi L. Wang, Dominic Yin, Kakali Ghoshal, Rida Mourad, Ambra Pozzi, Carmen M. Halabi, Lawrence H. Young, Hongyu Zhao, Le Zhang, Rui B. Chang

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10490-ySystems-level analyses of organ intrinsic nervous systems reveal that these networks are initially configured by lineage-dependent programmes, and their architecture and molecular identity are refined by intra-organ specific (...)

Nature

SNOR promotes translation restart after dormancy

mercredi 13 mai 2026 par Maciej Gluc, Higor Rosa, Maria Bozko, Lesley A. Turner, Cassidy R. Prince, Yelena Peskova, Heather A. Feaga, Kathleen L. Gould, Simone Mattei, Ahmad Jomaa

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10530-7High-resolution in situ cryo-electron tomography in Schizosaccharomyces pombe identifies SNOR protein, which binds to ribosomes during dormancy induced by glucose depletion, priming them for rapid reactivation of protein (...)

Nature

Ecotypes of triple-negative breast cancer in response to chemotherapy

mercredi 13 mai 2026 par Yun Yan, Yiyun Lin, Tapsi Kumar, Shanshan Bai, Aatish Thennavan, Jianzhuo Li, Emi Sei, Tuan Tran, Min Hu, Mitchell Rao, Chenling Tang, Siyuan He, Anna Casasent, Elizabeth Ravenberg, Gaiane Margishvili Rauch, Alyson R. Clayborn, Debu Tripathy, Alastair Thompson, Bora Lim, Lei Huo, Stacy Moulder, Clinton Yam, Nicholas Navin

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10469-9Treatment data for triple-negative breast cancer show the importance of macrophage subtypes and cancer-cell metaprograms for interferon signalling, HLA expression and cell cycle activity that are associated with a good (...)

Nature

Gaussian boson sampling with 1,024 squeezed states in 8,176 modes

mercredi 13 mai 2026 par Hua-Liang Liu, Hao Su, Yu-Hao Deng, Si-Qiu Gong, Yi-Chao Gu, Hao-Yang Tang, Meng-Hao Jia, Qian Wei, Yu-Kun Song, Dong-Zhou Wang, Ming-Yang Zheng, Fa-Xi Chen, Li-Bo Li, Si-Yu Ren, Xue-Zhi Zhu, Mei-Hong Wang, Yao-Jian Chen, Yan-Fei Liu, Long-Sheng Song, Peng-Yu Yang, Jun-Shi Chen, Hong An, Lei Zhang, Lin Gan, Guang-wen Yang, Jia-Min Xu, Yu-Ming He, Hui Wang, Han-Sen Zhong, Ming-Cheng Chen, Xiao Jiang, Li Li, Nai-Le Liu, Xiao-Long Su, Qiang Zhang, Chao-Yang Lu, Jian-Wei Pan

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10523-6A programmable photonic quantum processor, Jiuzhang 4.0, incorporates 1,024 high-efficiency squeezed states into a hybrid spatial–temporal encoded 8,176-mode (...)

Nature

Enamel proteins from six Homo erectus specimens across China

mercredi 13 mai 2026 par Qiaomei Fu, Zhongyou Wu, E. Andrew Bennett, Song Xing, Qiang Ji, Zhe Dong, Huiyun Rao, Xuejun Gu, Yizhao Dang, Jun Xing, Kai Zhou, Xiaotian Feng

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10478-8Palaeoproteomic analysis of ancient enamel proteins extracted from Middle Pleistocene Homo erectus specimens from the Zhoukoudian, Hexian and Sunjiadong sites in China suggests that they are a new genetic monogroup, and (...)

Nature