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Genetic architecture of sugarcane traits in a polyploid genomics framework

mercredi 27 mai 2026 par Jungang Wang, Xiaofeng Li, Yibin Wang, Jishan Lin, Shuai Chen, Hongbo Liu, Xiao Chen, Kun Chai, Aoqian Dong, Tingting Zhao, Cuilian Feng, Ruijie Wu, Ping Zhao, Yaodong Zheng, Zhongqiang Xia, Shengcheng Zhang, Yi Liu, Shenyang Qu, Ziqi Ye, Yuhan Song, Qingyuan Deng, Xiaofei Zeng, Guangrun Yu, Ran Kong, Baoqing Zhang, Wei Zhang, Peifang Zhao, Jun Mao, Xin Lu, Haifeng Jia, Xueting Zhao, Qianqian Zhang, Shuzhen Zhang, Wenwei Cai, Dongao Huo, Ling Li, Yuqing Gong, Shiqiang Huang, Yongji Huang, Zehuai Yu, Zuhu Deng, Baoshan Chen, Yuebin Zhang, Muqing Zhang, Ray Ming, Xingtan Zhang

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10576-7A fully phased genome assembly of the sugarcane foundational cultivar POJ2878 reveals extensive subgenome recombination and non-homologous chromosomal rearrangements.

Nature

Universal transcriptomic hallmarks of mammalian ageing and mortality

mercredi 27 mai 2026 par Alexander Tyshkovskiy, Daria Kholdina, Maria Davitadze, Adrian Molière, Alibek Moldakozhayev, Yoshiyasu Tongu, Tomoko Kasahara, Dmitrii Glubokov, Alec Eames, Leonid M. Kats, Anastasiya Vladimirova, Kejun Ying, Hanna Liu, Bohan Zhang, Uma Khasanova, Mahdi Moqri, Jeremy M. Van Raamsdonk, David E. Harrison, Randy Strong, Takaaki Abe, Sergey E. Dmitriev, Vadim N. Gladyshev

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10542-3Integration of gene expression data from multiple tissues across four mammalian species reveals conserved transcriptomic signatures of mammalian ageing and mortality and uncovers the modular architecture of ageing and (...)

Nature

Substrate selectivity of the human RNA m⁵C methyltransferase NSUN2

mercredi 27 mai 2026 par Jacob Canepa, Victor M. Ruiz-Arroyo, Netanya S. Schlamowitz, Yunsun Nam

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10582-9NSUN2 is an enzyme that adds a small chemical mark to RNA molecules and uniquely selects its targets based on specific sequence patterns and structural features.

Nature

Transcription factor codes patterning neuronal groundplans of the cerebrum

mercredi 27 mai 2026 par Najia A. Elkahlah, Yunzhi Lin, Yijie Pan, Joseph A. Carter, Troy R. Shirangi, E. Josephine Clowney

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10526-3Researchers mapped how transcription factors define neuron lineages in fruit fly brains, revealing hierarchical genetic programs that shape and specialize circuits controlling motivated behaviours such as (...)

Nature

Dynamical freezing for magnetometry in an interacting spin ensemble

mercredi 27 mai 2026 par Ya-Nan Lu, Dong Yuan, Yixuan Ma, Yan-Qing Liu, Si Jiang, Xiang-Qian Meng, Yi-Jie Xu, Xiu-Ying Chang, Chong Zu, Hong-Zheng Zhao, Dong-Ling Deng, Lu-Ming Duan, Pan-Yu Hou

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10585-6Dynamical freezing, a mechanism by which a driven quantum system may not thermalize to a featureless ‘infinite-temperature’ state at long times, is experimentally observed in an ensemble of interacting nitrogen-vacancy spins in (...)

Nature

Spatiotemporal transcriptome atlas of human embryos after gastrulation

mercredi 27 mai 2026 par Jiexue Pan, Yuejiao Li, Zhongliang Lin, Qing Lan, Ying Zhang, Huixi Chen, Shengwei Sui, Man Zhai, Gaochen Zhang, Yi Cheng, Yunhui Tang, Qingchen Wang, Yue Xu, Guoling Li, Chunyan Xu, Haoqi Yan, Yiting Mao, Xingxia Wang, Hao Li, Yiping Zhu, Qinfang Chen, Yichun Guan, Nan Meng, Chang Wang, Haiqian Lu, Xiangjuan Li, Tingting Zheng, Xiaoying Yao, Tingyu Yang, Xuan Chen, Qiuyu Qin, Bin Jiang, Yuxing Ren, Xinmei Liu, Yuxin Zhang, Minghui Yu, Lifang Wang, Yanrong Wei, Meiqi Luo, Ji Nancuo, Fuhe Ma, Ziwei Wang, Zhihua Ou, Ying Lei, Xin Jin, Jianzhong Sheng, Congjian Xu, Yanting Wu, Chenming Xu, Lijian Zhao, Hongbo Yang, Ya Gao, Guolian Ding, Xun Xu, Hefeng Huang

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10545-0A spatiotemporal transcriptome atlas of whole-human embryos after gastrulation and previously transcriptionally undescribed stages of human development are (...)

Nature

Cavity-driven attractive interactions in quantum materials

mercredi 27 mai 2026 par F. Helmrich, H. S. Adlong, M. Kroner, I. Khanonkin, G. Scalari, J. Faist, A. ?mamo?lu, T. F. Nova

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10609-1A broadband, sub-wavelength time-domain microscope is described, enabling the observation that terahertz light trapped within a cavity can mediate attractive interactions in a tunable van der Waals (...)

Nature

Experimental randomness amplification

mercredi 27 mai 2026 par Anatoly Kulikov, Simon Storz, Josua D. Schär, Martin Sandfuchs, Ramona Wolf, Florence Berterottière, Christoph Hellings, Andreas Wallraff, Renato Renner

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10521-8An experimental realization of device-independent randomness amplification is demonstrated using superconducting qubits, in which a source of weak, correlated randomness is converted into virtually perfect random bits, (...)

Nature

Redesigning algorithms to intervene on social norm misperceptions during a national election

mercredi 27 mai 2026 par William J. Brady, Meriel Doyle, Abdo Elnakouri, Eli J. Finkel, Joshua Conrad Jackson, Nour Kteily, Victoria Parker, Curtis Puryear, Trevor Spelman, Jacob Teeny, Mark Torres

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10536-1Engagement-based feeds amplify intergroup, moralized, emotional (IME) and toxic content relative to reverse-chronological feeds, and a diversified extremity algorithm reduces exposure to IME and toxic content while maintaining (...)

Nature

Mechanism of age-related accumulation of mtDNA mutations in human blood

mercredi 27 mai 2026 par Rahul Gupta, Timothy J. Durham, Grant Chau, Masahiro Kanai, Md Mesbah Uddin, Wenhan Lu, M. Austin Argentieri, Konrad J. Karczewski, Daniel Howrigan, Pradeep Natarajan, Wei Zhou, Benjamin M. Neale, Vamsi K. Mootha

Nature, Published online: 27 May 2026; doi:10.1038/s41586-026-10569-6Genome-wide analyses indicate that accumulation of mitochondrial DNA mutations, a hallmark of ageing, may be caused by cryptic replication errors, which act as passenger mutations that eventually become detectable with age (...)

Nature