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Daily briefing: CAR-T-cell therapy recipient nears two decades in cancer remission

mardi 18 février 2025 par Jacob Smith

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00522-4A woman who received CAR-T-cell therapy has now been in cancer remission for 19 years. Plus, a genetic swap makes mice squeak differently.

Nature

Migraine is more than a headache — a radical rethink offers hope to one billion people

mardi 18 février 2025 par Fred Schwaller

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00456-xDrugs that can prevent or relieve migraine attacks are only effective for some people. Research is starting to untangle the reasons why.

Nature

Molecular glue unexpectedly mimics the effect of cancer mutations

mardi 18 février 2025 par Jonathan W. Bushman, Patrick Ryan Potts

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00090-7Many conventional small-molecule drugs work by inhibiting proteins, affecting their function. One small molecule instead imbues a protein with a new function in a mechanism that could inform rational drug (...)

Nature

Why is it so hard to rewrite a genome?

mardi 18 février 2025 par Michael Eisenstein

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00462-zSynthetic biologists have the know-how and ambition to retool whole genomes. But the hidden complexity of biological systems continues to surprise them.

Nature

Pinpointing neurons that hinder cancer treatment

mardi 18 février 2025 par Ihsan Ekin Demir, Elke Demir

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00501-9Pancreatic tumours hijack neuronal signalling mechanisms to boost cancer growth. A technology to identify and profile mouse neurons that connect the spinal cord to pancreatic cancer might improve treatment of this (...)

Nature

Don’t overlook the mental-health costs of California’s wildfires

mardi 18 février 2025 par Shir Mor-Ben-Ishai, Yafit Levin, Menachem Ben-Ezra

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00496-3Don’t overlook the mental-health costs of California’s wildfires

Nature

A giant leap for machine translation could be even bigger

mardi 18 février 2025 par Chao Su

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00497-2A giant leap for machine translation could be even bigger

Nature

Charles Darwin saw the importance of development in evolution

mardi 18 février 2025 par Yongsheng Liu

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00495-4Charles Darwin saw the importance of development in evolution

Nature

A sustainable ocean needs thriving ocean societies

mardi 18 février 2025 par Joachim Claudet, Jessica Blythe, David Gill

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00494-5A sustainable ocean needs thriving ocean societies

Nature

A human gene makes mice squeak differently — did it contribute to language?

mardi 18 février 2025 par Ewen Callaway

Nature, Published online: 18 February 2025; doi:10.1038/d41586-025-00518-0A gene variant present in most people might have contributed to cognitive differences between humans and their closest relatives.

Nature