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Clues to the sloth’s sloth found in its genome

jeudi 18 juin 2026

Nature, Published online: 18 June 2026; doi:10.1038/d41586-026-01869-ySequencing shows duplication of genes that affect mitochondria, the organelles that provide energy for cells.

Nature

Fast formation to reinforce lithium-rich cathodes

mercredi 17 juin 2026 par Mengjian Fan, Jiantao Li, Guiyang Gao, Benli Jiang, Longlong Fan, Qingxi Yuan, Yinggan Zhang, Hongfei Zheng, Saichao Li, Liang Lin, Zonghai Chen, Yang Ren, Yuanyuan Liu, Wei He, Gaosheng Chen, Baisheng Sa, Laisen Wang, Jie Lin, Dong-Liang Peng, Qingshui Xie

Nature, Published online: 17 June 2026; doi:10.1038/s41586-025-09553-3Fast formation in lithium-ion batteries outperforms conventional slow formation, lowering costs and improving battery capacity, stability and cycle life, offering broader application to electrode (...)

Nature

Revealing competitive interfacial reactions in high-energy Li–S batteries

mercredi 17 juin 2026 par Shiyuan Zhou, Fei Pei, Qizheng Zheng, Gen Li, Hongyuan Yi, Linzhi Chen, Shi Tang, Qi Kang, Zu-Wei Yin, Sangui Liu, Liangping Xiao, Ling Huang, Yu Qiao, Yunhui Huang, Shi-Gang Sun, Hong-Gang Liao

Nature, Published online: 17 June 2026; doi:10.1038/s41586-025-09473-2Visualization of concentration-driven phase segregation within high-concentration interfacial layers in the context of high-energy lithium–sulfur batteries using liquid-cell electrochemical transmission electron microscopy (...)

Nature

Molecular basis of polyadenylated RNA fate determination in the nucleus

mercredi 17 juin 2026 par Andrii Bugai, Ulrich Hohmann, Ana Lorenzo, Max Graf, Laura Fin, Jérôme O. Rouvière, Laszlo Tirian, Yuhui Dou, Marion Le Rest, Patrik Polák, Dennis Johnsen, Lis Jakobsen, Jens Skorstengaard Andersen, Julius Brennecke, Clemens Plaschka, Torben Heick Jensen

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10650-0Biochemical, structural and cell biological analyses reveal that UAP56 (DDX39B) assembles with a TREX-2–like module that redirects non-functional polyadenylated RNAs from export to (...)

Nature

Rock weathering can counteract river CO₂ emissions induced by permafrost thaw

mercredi 17 juin 2026 par Liwei Zhang, Aaron Bufe, Joshua F. Dean, Gerard Rocher-Ros, Ryan A. Sponseller, Emily H. Stanley, Jan Karlsson, David E. Butman, Ran Liu, Lijun Hou, Jinzhi Ding, Shilong Piao, Xinghui Xia, Tom J. Battin

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10664-8Permafrost thaw on the Qinghai–Tibet Plateau increases rock-weathering rates while reducing river CO2 emissions, suggesting geological carbon fluxes may eventually outpace thaw-driven (...)

Nature

A blastoporal organizer in a ctenophore

mercredi 17 juin 2026 par Stanislav Kremnyov, Tatiana Lebedeva, Grigory Genikhovich, Andreas Hejnol

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10643-zExperiments using the comb jelly Mnemiopsis leidyi and the sea anemone Nematostella vectensis reveal that the emergence of a core signalling pathway may have been a key innovation enabling the transition to multicellularity (...)

Nature

Confined migration induces non-lethal DNA damage in developing neurons

mercredi 17 juin 2026 par Zhejing Zhang, Andres Canela, Junko Kurisu, Peilin Zou, Takumi Kawaue, Naotaka Nakazawa, Noriko Takeda, Mai Saeki, Masaki Utsunomiya, Merve Bilgic, Fumiyoshi Ishidate, Gianluca Grenci, Takahiro Furuta, Yusuke Kishi, Hiroyuki Sasanuma, Mineko Kengaku

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10648-8The migration of neurons in developing cerebral and cerebellar cortices is accompanied by massive DNA double-strand breaks due to mechanostress during passage through narrow interstitial (...)

Nature

Mapping the neuronal building blocks of human language with language models

mercredi 17 juin 2026 par Jing Cai, Yoav Kfir, Mohsen Jamali, Hesen Huang, Young Joon Kim, Sydney S. Cash, Ziv M. Williams

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10691-5Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the higher-order syntactic structure of (...)

Nature

Cortical development dynamics across autism spectrum disorder mouse models

mercredi 17 juin 2026 par Lena A. Schwarz, Christoph P. Dotter, Sergey Isaev, Michela Lisi, Daniel Malzl, Christoph Büschl, Sabrina Ladstätter, Bárbara Oliveira, Matteo Barel, Bernadette Basilico, Chaitanya Chintaluri, Sarah Gorkiewicz, Mohammad Goudarzi, Tereza Belinova, Stephan Reichl, Gintar? Sendžikait?, Satish Arcot Jayaram, Peter Koppensteiner, Christoph Sommer, Tim P. Vogels, Jörg Menche, Igor Adameyko, Peter V. Kharchenko, Christoph Bock, Gaia Novarino

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10679-1Using single-nucleus multi-omic sequencing, diverse autism spectrum disorder-linked gene mutations converge on transient, stage-specific disruptions in early brain development, and highlight sex-specific gene expression (...)

Nature

Analysis of 173,303 exomes and genomes in the Pakistan Genome Resource

mercredi 17 juin 2026 par Christopher Koch, Shareef Khalid, Maleeha Zaman Khan, Shruthi Bandyadka, Brian Doyon, Daniel P. Denning, Muhammad Jahanzaib, Muhammad Rehan Mian, Wafa Gul, Muhammad Bilal Liaqat, Aneeqa Bano, Marium Dahar, Namra Saqib, Lubna Kamani, Nazish Butt, Anjum Jalal, Riffat Sultana, Shahid Abbas, Musfireh Siddiqeh, Muhammad Haroon, Asadullah Khan, Khalid Parvez Babar, Aflak Rasheed, Javed Iqbal, Faizan Aslam, Umar Usman, Muhammad Akram Bajwa, Ali Hyder, Muhammad Sadik Memon, Nauman Hashmani, Mohsin Iqbal Haroon, Ambreen Muddassir, Syed Asif Raza Zaidi, Mateen Akram, Muhammad Hussain, Saima Naz Mohsin, Samreen Bugti, Tariq Mehmood, Abdul Lateef Rodeni, Shahid Mukhtar, Tahir Rasool, Adil Mahmood, Muhammad Noor Wazir, Sheraz Jamal Khan, Muhammad Asghar Khan, Rahmat Ghaffar, Sanaullah Jan, Noor Ul Hadi, Roshina Anjum, Rehan Abdullah, Muhammad Usman Musharraf, Muhammad Tahir Bashir, Muhammad Ali, Irfan Majeed, Muhammad Haroon Bilal, Shahzad Ali Khan, Chihiro Hata, Ikuyo Kou, Makoto Asaumi, Wataru Morii, Katherine R. Smith, Kousik Kundu, Kieren Lythgow, Stewart MacArthur, Sebastian Wasilewski, Slavé Petrovski, Aris Baras, Gonçalo Abecasis, Adolfo Ferrando, Giovanni Coppola, Andrew Deubler, Luca A. Lotta, John D. Overton, Jeffrey G. Reid, Alan Shuldiner, Katherine Siminovitch, Jason Portnoy, Marcus B. Jones, Lyndon Mitnaul, Alison Fenney, Jonathan Marchini, Manuel Allen Revez Ferreira, Maya Ghoussaini, Mona Nafde, William Salerno, Cristen Willer, Lourdes Crane, Christina Beechert, Erin Fuller, Laura M. Cremona, Eugene Kalyuskin, Hang Du, Caitlin Forsythe, Zhenhua Gu, Kristy Guevara, Michael Lattari, Alexander Lopez, Kia Manoochehri, Prathyusha Challa, Manasi Pradhan, Raymond Reynoso, Ricardo Schiavo, Maria Sotiropoulos Padilla, Chenggu Wang, Sarah E. Wolf, Manan Goyal, George Mitra, Sanjay Sreeram, Rouel Lanche, Vrushali Mahajan, Sai Lakshmi Vasireddy, Gisu Eom, Krishna Pawan Punuru, Sujit Gokhale, Benjamin Sultan, Pooja Mule, Mudasar Sarwar, Muhammad Aqeel, Xiaodong Bai, Lance Zhang, Sean O’Keeffe, Razvan Panea, Evan Edelstein, Ayesha Rasool, Evan K. Maxwell, Boris Boutkov, Alexander Gorovits, Ju Guan, Lukas Habegger, Alicia Hawes, Olga Krasheninina, Samantha Zarate, Adam J. Mansfield, Joshua Backman, Kathy Burch, Adrian Campos, Liron Ganel, Sheila Gaynor, Benjamin Geraghty, Arkopravo Ghosh, Salvador Romero Martinez, Christopher Gillies, Lauren Gurski, Eric Jorgenson, Tyler Joseph, Michael Kessler, Jack Kosmicki, Adam Locke, Priyanka Nakka, Karl Landheer, Olivier Delaneau, Anthony Marcketta, Joelle Mbatchou, Arden Moscati, Anita Pandit, Jonathan Ross, Carlo Sidore, Eli Stahl, Timothy Thornton, Sailaja Vedantam, Rujin Wang, Kuan-Han Wu, Bin Ye, Blair Zhang, Andrey Ziyatdinov, Yuxin Zou, Jingning Zhang, Kyoko Watanabe, Mira Tang, Frank Wendt, Suganthi Balasubramanian, Suying Bao, Kathie Sun, Chuanyi Zhang, Sean Yu, Aaron Zhang, David Corrigan, Dhruv Shidhaye, Chen Wang, Keyrun Adhikari, Alexander Lachmann, Brian Hobbs, Jon Silver, William Palmer, Rita Guerreiro, Amit Joshi, Antoine Baldassari, Sarah Graham, Ernst Mayerhofer, Erola Pairo Castineira, Mary Haas, Niek Verweij, George Hindy, Jonas Bovijn, Tanima De, Luanluan Sun, Olukayode Sosina, Arthur Gilly, Peter Dornbos, Juan Rodriguez-Flores, Gannie Tzoneva, Momodou W. Jallow, Anna Alkelai, Ariane Ayer, Veera Rajagopal, Sahar Gelfman, Vijay Kumar, Jacqueline Otto, Jose Bras, Silvia Alvarez, Jessie Brown, Hossein Khiabanian, Joana Revez, Kimberly Skead, Valentina Zavala, Jae Soon Sul, Lei Chen, Sam Choi, Amy Damask, Nan Lin, Charles Paulding, Sameer Malhotra, Joseph Herman, Michelle G. LeBlanc, Nadia Rana, Jennifer Rico-Varela, Jaimee Hernandez, Larizbeth Romero, Ashley Paynter, Randi Schwartz, Jody Hankins, Anna Han, Samuel Hart, Ryan Smith, Ann Perez-Beals, Gina Solari, Johannie Rivera-Picart, Michelle Pagan, Sunilbe Siceron, Juan L. Rodriguez-Flores, Moeen Riaz, Manav Kapoor, Joshua D. Backman, Alan R. Shuldiner, James E. Bradner, Igor Splawski, Asif Rasheed, John E. Dominy, Allan M. Gurtan, Danish Saleheen

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10667-5The Pakistan Genome Resource compiles biobank data from 173,303 individuals with high familial relatedness, broadening the catalogue of human genetic variation and establishing a population-specific genomic reference for (...)

Nature