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Key process in sex-cell formation can finally be studied in vitro

mercredi 19 février 2025 par Francisco Mendez Diaz, Kevin D. Corbett

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00305-xThe enzyme SPO11 has a crucial role in meiosis, the process that forms sperm and egg cells. The activity of purified SPO11 has now been reconstituted in a cell-free system — enabling the enzyme’s role to be studied in (...)

Nature

Exclusive: These universities have the most retracted scientific articles

mercredi 19 février 2025 par Richard Van Noorden

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00455-yA first-of-its-kind analysis by Nature reveals which institutions are retraction hotspots.

Nature

Racial bias eliminated when ratings switch from five stars to thumbs up or down

mercredi 19 février 2025 par Lauren Rivera

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00304-yImplementing a performance-rating system with a two-point scale instead of a five-point scale could be an easy way to temper racial prejudices and tangibly improve income equality for workers from under-represented (...)

Nature

Why retractions data could be a powerful tool for cleaning up science

mercredi 19 février 2025

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00509-1A Nature analysis of retractions hotspots around the world suggests institutions should pay close attention to retractions data.

Nature

Putting the brakes on mitochondrial fusion to prevent escape of mitochondrial DNA

mercredi 19 février 2025 par Kate McArthur, Michael T. Ryan

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00303-zCellular organelles called mitochondria contain DNA and can fuse together or split apart. It emerges that excess fusion is averted by stress-activated regulators, preventing the potentially harmful release of (...)

Nature

Women need platforms to celebrate excellence in research and technology

mercredi 19 février 2025

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00510-8Nature is proud to be associated with a new award for women in technology. The world needs more prizes for exceptional researchers and innovators.

Nature

Why these scientists devote time to editing and updating Wikipedia

mercredi 19 février 2025 par Christine Ro

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00244-7Researchers can recognize a reliable source of information, making them ideal contributors to the free global online encyclopaedia.

Nature

Bespoke vaccines can elicit long-lived immune activity against pancreatic cancer

mercredi 19 février 2025

Nature, Published online: 19 February 2025; doi:10.1038/d41586-025-00470-zCancer vaccines must induce immune cells, called CD8+ T cells, that can recognize cancer cells over the long term. In pancreatic cancer, a common and deadly cancer, RNA vaccines that encode neoantigens — mutant proteins (...)

Nature

Artificial intelligence for modelling infectious disease epidemics

mercredi 19 février 2025 par Moritz U. G. Kraemer, Joseph L.-H. Tsui, Serina Y. Chang, Spyros Lytras, Mark P. Khurana, Samantha Vanderslott, Sumali Bajaj, Neil Scheidwasser, Jacob Liam Curran-Sebastian, Elizaveta Semenova, Mengyan Zhang, H. Juliette T. Unwin, Oliver J. Watson, Cathal Mills, Abhishek Dasgupta, Luca Ferretti, Samuel V. Scarpino, Etien Koua, Oliver Morgan, Houriiyah Tegally, Ulrich Paquet, Loukas Moutsianas, Christophe Fraser, Neil M. Ferguson, Eric J. Topol, David A. Duchêne, Tanja Stadler, Patricia Kingori, Michael J. Parker, Francesca Dominici, Nigel Shadbolt, Marc A. Suchard, Oliver Ratmann, Seth Flaxman, Edward C. Holmes, Manuel Gomez-Rodriguez, Bernhard Schölkopf, Christl A. Donnelly, Oliver G. Pybus, Simon Cauchemez, Samir Bhatt

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08564-wThis Perspective considers the application to infectious disease modelling of AI systems that combine machine learning, computational statistics, information retrieval and data (...)

Nature

Community estimate of global glacier mass changes from 2000 to 2023

mercredi 19 février 2025 par Michael Zemp, Livia Jakob, Inés Dussaillant, Samuel U. Nussbaumer, Noel Gourmelen, Sophie Dubber, Geruo A, Sahra Abdullahi, Liss Marie Andreassen, Etienne Berthier, Atanu Bhattacharya, Alejandro Blazquez, Laura F. Boehm Vock, Tobias Bolch, Jason Box, Matthias H. Braun, Fanny Brun, Eric Cicero, William Colgan, Nicolas Eckert, Daniel Farinotti, Caitlyn Florentine, Dana Floricioiu, Alex Gardner, Christopher Harig, Javed Hassan, Romain Hugonnet, Matthias Huss, Tómas Jóhannesson, Chia-Chun Angela Liang, Chang-Qing Ke, Shfaqat Abbas Khan, Owen King, Marin Kneib, Lukas Krieger, Fabien Maussion, Enrico Mattea, Robert McNabb, Brian Menounos, Evan Miles, Geir Moholdt, Johan Nilsson, Finnur Pálsson, Julia Pfeffer, Livia Piermattei, Stephen Plummer, Andreas Richter, Ingo Sasgen, Lilian Schuster, Thorsten Seehaus, Xiaoyi Shen, Christian Sommer, Tyler Sutterley, Désirée Treichler, Isabella Velicogna, Bert Wouters, Harry Zekollari, Whyjay Zheng

Nature, Published online: 19 February 2025; doi:10.1038/s41586-024-08545-zAn intercomparison exercise reassesses mass loss from glaciers worldwide based on the main in situ and satellite methods from 2000 to 2023; the results are consistent with previous assessments and provide a refined and (...)

Nature