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Molecular profiling of gene-edited cells reveals shared drug-resistance mechanisms

mercredi 15 avril 2026
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01181-9A platform for tracking the changes in gene expression and chromatin accessibility that follow interference with specific genes has been developed. The platform, called PerturbFate, was applied to skin-cancer cells and (...)

Here are the top locations for cancer research in the Nature Index

mercredi 15 avril 2026
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00690-xA breakdown of publications in the database also reveals the cancer types with the highest output.

I was set to lead an undergraduate research trip abroad. Then my visa was denied

mercredi 15 avril 2026 par Mayank Chugh
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00403-4Through flexibility, problem-solving and the generosity of colleagues, I shepherded students through fieldwork remotely.

AI speeds up design of devices that turn waste heat into electricity

mercredi 15 avril 2026 par Jing Cao, Ady Suwardi
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00907-zAn artificial-intelligence system bypasses complex equations to predict the performance of thermoelectric generators.

Four rising stars shaping the future of cancer research

mercredi 15 avril 2026 par Sandy Ong, Amanda Heidt
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-00688-5Meet the creative minds that aim to improve cancer detection and treatment.

What China’s Great Green Wall can teach the world

mercredi 15 avril 2026
Nature, Published online: 15 April 2026; doi:10.1038/d41586-026-01195-3Efforts to boost tree cover and restore degraded land globally need stable funding and time to learn from failure.

Composable neural emulators accelerate thermoelectric generator design

mercredi 15 avril 2026 par Airan Li, Xinzhi Wu, Longquan Wang, Gang Wu, Jiankang Li, Zhao Hu, Xinyuan Wang, Takao Mori
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10223-1A composable neural network emulator is described for speeding up thermoelectric generator design, demonstrating the ability to predict generator performance with >99% accuracy while taking only 0.01% of the time compared (...)

EBV strain interacts with host HLA to drive nasopharyngeal carcinoma risk

mercredi 15 avril 2026 par Yanhong Chen, Jingtong Liang, Wanlin Zhang, Xinyu Zhang, Xinyi Zhang, Ching-Yuan Wang, Fei Yao, Shanshan Zhang, Xiang Zhou, Weimin Ye, Ruimei Feng, Yonglin Cai, Zhe Zhang, Mingfang Ji, Qian Cui, Xihong Lin, Jiesen Li, Jialei Xu, Qiuting Zhang, Qinyao Huang, Yingying Cheng, Yanran Luo, Xiaoping Ye, Qisheng Feng, Minzhong Tang, Mu-Sheng Zeng, Yi-Xin Zeng, Zhonghua Liu, Weiwei Zhai, Jianjun Liu, Miao Xu
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10416-8A genome-to-genome association study identifies host and viral risk factors that interact to drive nasopharyngeal carcinoma endemicity in southern China.

Mapping convergent regulators of melanoma drug resistance by PerturbFate

mercredi 15 avril 2026 par Zihan Xu, Ziyu Lu, Aileen Ugurbil, Abdulraouf Abdulraouf, Andrew Liao, Jianxiang Zhang, Wei Zhou, Junyue Cao
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10367-0PerturbFate is a high-throughput, cost-effective, single-cell platform that systematically profiles CRISPR interference perturbations to reveal common regulatory nodes and convergent phenotypic states across diverse genetic (...)

Imaging interface-controlled bulk oxygen spillover

mercredi 15 avril 2026 par Weijue Wang, Hongbin Xu, Shuhui Liu, Xiaofeng Yang, Wei Liu, Yang-Gang Wang, Yanqiang Huang, Tao Zhang
Nature, Published online: 15 April 2026; doi:10.1038/s41586-026-10324-xIn situ microscopic single-particle imaging demonstrates the significance of rationally engineered metal–support interfaces for activating the oxygen in bulk catalyst, helping elucidate reaction pathways in catalytic (...)

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