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Four-component protein nanocages designed by programmed symmetry breaking

mercredi 18 décembre 2024 par Sangmin Lee, Ryan D. Kibler, Green Ahn, Yang Hsia, Andrew J. Borst, Annika Philomin, Madison A. Kennedy, Buwei Huang, Barry Stoddard, David Baker

Nature, Published online: 18 December 2024; doi:10.1038/s41586-024-07814-1Using viral capsid architectures as template for design, higher triangulation number nanocages that require symmetry breaking offer potential advances in targeted delivery and antigen-displaying (...)

Nature

A dormant overmassive black hole in the early Universe

mercredi 18 décembre 2024 par Ignas Juodžbalis, Roberto Maiolino, William M. Baker, Sandro Tacchella, Jan Scholtz, Francesco D’Eugenio, Joris Witstok, Raffaella Schneider, Alessandro Trinca, Rosa Valiante, Christa DeCoursey, Mirko Curti, Stefano Carniani, Jacopo Chevallard, Anna de Graaff, Santiago Arribas, Jake S. Bennett, Martin A. Bourne, Andrew J. Bunker, Stéphane Charlot, Brian Jiang, Sophie Koudmani, Michele Perna, Brant Robertson, Debora Sijacki, Hannah Übler, Christina C. Williams, Chris Willott

Nature, Published online: 18 December 2024; doi:10.1038/s41586-024-08210-5A dormant supermassive black hole at high redshift that is substantially overmassive relative to its host galaxy has been detected, indicating a much larger population of dormant black holes around the epoch of (...)

Nature

Machine learning helps to determine the diverse conformations of RNA molecules

mercredi 18 décembre 2024

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04134-2An innovative technique called HORNET uses atomic force microscopy and a machine-learning architecture called a deep neural network to recapitulate the 3D structures of individual RNA molecules. This method enables the (...)

Nature

The small-drone revolution is coming — scientists need to ensure it will be safe

mercredi 18 décembre 2024 par Xun Huang

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04167-7China’s low-altitude aviation economy is poised to become a trillion-yuan industry in 2025 — if safety and security challenges can be overcome.

Nature

Vapour-deposited thin films raise the possibility of portable nuclear clocks

mercredi 18 décembre 2024

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04125-3A rare isotope, thorium-229, exhibits a unique low-energy nuclear transition that could form the basis of a precise nuclear clock. Observation of this transition in vapour-deposited thin films, which require only (...)

Nature

In the space between the seconds

mercredi 18 décembre 2024 par Jenny Rae Rappaport

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04073-yWhen the party’s over.

Nature

Sea ice is shrinking during Antarctic winter: here’s what it means for Earth’s oceans and atmosphere

mercredi 18 décembre 2024 par Laura L. Landrum, Alice. K. DuVivier

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04078-7The extent of Antarctic sea ice dropped precipitously in 2023. Analysis shows that this decline has increased the transfer of ocean heat to the atmosphere — in turn affecting ocean circulation and the frequency of (...)

Nature

Controversial COVID study that promoted unproven treatment retracted after four-year saga

mercredi 18 décembre 2024 par Richard Van Noorden

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04014-9Paper on hydroxychloroquine led by French researcher Didier Raoult is second-most-cited study ever to be withdrawn.

Nature

Simultaneous phase transition and chemical reaction in a heat-storing material

mercredi 18 décembre 2024

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04128-0Materials that store thermal energy can be used to gather and retain large amounts of the renewable energy that is generated by wind and Sun. The creation of materials that are highly thermal-energy dense can now be (...)

Nature

How car and battery companies can work around US trade tariffs and rules

mercredi 18 décembre 2024 par Hyeon Young Chun, Tae Jung Park

Nature, Published online: 18 December 2024; doi:10.1038/d41586-024-04168-6Understanding China’s and other nations’ responses to US trade measures can help policymakers and firms find ways to manage economic competition.

Nature