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Abyssal ocean overturning slowdown and warming driven by Antarctic meltwater

mercredi 29 mars 2023 par Qian Li, Matthew H. England, Andrew McC. Hogg, Stephen R. Rintoul, Adele K. Morrison
Nature, Published online: 29 March 2023; doi:10.1038/s41586-023-05762-wSimulations show that projected increases in Antarctic meltwater will slow down the abyssal ocean overturning circulation over the coming decades and lead to warming and ageing of the ocean (...)

An atlas of genetic scores to predict multi-omic traits

mercredi 29 mars 2023 par Yu Xu, Scott C. Ritchie, Yujian Liang, Paul R. H. J. Timmers, Maik Pietzner, Loïc Lannelongue, Samuel A. Lambert, Usman A. Tahir, Sebastian May-Wilson, Carles Foguet, Åsa Johansson, Praveen Surendran, Artika P. Nath, Elodie Persyn, James E. Peters, Clare Oliver-Williams, Shuliang Deng, Bram Prins, Jian’an Luan, Lorenzo Bomba, Nicole Soranzo, Emanuele Di Angelantonio, Nicola Pirastu, E. Shyong Tai, Rob M. van Dam, Helen Parkinson, Emma E. Davenport, Dirk S. Paul, Christopher Yau, Robert E. Gerszten, Anders Mälarstig, John Danesh, Xueling Sim, Claudia Langenberg, James F. Wilson, Adam S. Butterworth, Michael Inouye
Nature, Published online: 29 March 2023; doi:10.1038/s41586-023-05844-9A machine learning approach is used to analyse multi-omics (proteomics, metabolomics and transcriptomics) data, producing genetic scores for more than 17,000 biomolecular traits in human blood, and identifying possible (...)

Spatial multiomics map of trophoblast development in early pregnancy

mercredi 29 mars 2023 par Anna Arutyunyan, Kenny Roberts, Kevin Troulé, Frederick C. K. Wong, Megan A. Sheridan, Ilia Kats, Luz Garcia-Alonso, Britta Velten, Regina Hoo, Elias R. Ruiz-Morales, Carmen Sancho-Serra, Jarrod Shilts, Louis-Francois Handfield, Luca Marconato, Elizabeth Tuck, Lucy Gardner, Cecilia Icoresi Mazzeo, Qian Li, Iva Kelava, Gavin J. Wright, Elena Prigmore, Sarah A. Teichmann, Omer Ali Bayraktar, Ashley Moffett, Oliver Stegle, Margherita Y. Turco, Roser Vento-Tormo
Nature, Published online: 29 March 2023; doi:10.1038/s41586-023-05869-0A multiomics single-cell atlas of the human maternal–fetal interface including the myometrium, combining spatial transcriptomics data with chromatin accessibility, provides a comprehensive analysis of cell states as placental (...)

Genome-based scores predict thousands of molecular traits in humans

mercredi 29 mars 2023
Nature, Published online: 29 March 2023; doi:10.1038/d41586-023-00721-xGenetic scores for predicting levels of several types of biomolecule have been developed and validated in people of diverse ancestries, and used to uncover insights into disease biology. An open resource to disseminate these (...)

War of the Latitudes

mercredi 29 mars 2023 par Angela Hessler
Nature, Published online: 29 March 2023; doi:10.1038/d41586-023-00858-9A journey into danger.

Medieval Swahili people had both African and Asian ancestry

mercredi 29 mars 2023
Nature, Published online: 29 March 2023; doi:10.1038/d41586-023-00302-yAnalyses of ancient DNA from 80 individuals buried in medieval Swahili stone towns along the East African coast revealed that these individuals had both African and Asian ancestry. The findings suggest that in most cases, (...)

Could grinding up lithium batteries help to recycle them?

mercredi 29 mars 2023 par Katharine Sanderson
Nature, Published online: 29 March 2023; doi:10.1038/d41586-023-00915-3Researchers use ‘mechanochemistry’ to recover the metal from batteries at a small scale.

Southern Ocean heat sink hindered by melting ice

mercredi 29 mars 2023 par Joellen L. Russell
Nature, Published online: 29 March 2023; doi:10.1038/d41586-023-00835-2Simulations show that the melting of Antarctic ice reduces the production of deep water that stores heat at the bottom of the Southern Ocean. Comprehensive models could reveal whether the trend will (...)

What is acute kidney injury? A visual guide

mercredi 29 mars 2023 par Michael Eisenstein
Nature, Published online: 29 March 2023; doi:10.1038/d41586-023-00804-9Early detection and prompt treatment could prevent long-term health effects of acute kidney injury, a condition that commonly arises while people are in hospital.

Tracking cubic ice at molecular resolution

mercredi 29 mars 2023 par Xudan Huang, Lifen Wang, Keyang Liu, Lei Liao, Huacong Sun, Jianlin Wang, Xuezeng Tian, Zhi Xu, Wenlong Wang, Lei Liu, Ying Jiang, Ji Chen, Enge Wang, Xuedong Bai
Nature, Published online: 29 March 2023; doi:10.1038/s41586-023-05864-5Tracking the formation of cubic ice (ice Ic) using transmission electron microscopy and low-dose imaging shows preferential nucleation of ice Ic at low-temperature interfaces and two types of stacking (...)

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