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Warming and cooling catalyse widespread temporal turnover in biodiversity

mercredi 29 janvier 2025 par Malin L. Pinsky, Helmut Hillebrand, Jonathan M. Chase, Laura H. Antão, Myriam R. Hirt, Ulrich Brose, Michael T. Burrows, Benoit Gauzens, Benjamin Rosenbaum, Shane A. Blowes
Nature, Published online: 29 January 2025; doi:10.1038/s41586-024-08456-zGlobal-scale analyses of marine, terrestrial and freshwater assemblages found that temporal rates of species replacement were faster in locations with faster temperature change, including warming and cooling, and (...)

Structure and mechanism of vitamin-K-dependent ?-glutamyl carboxylase

mercredi 29 janvier 2025 par Rong Wang, Baozhi Chen, Nadia Elghobashi-Meinhardt, Jian-Ke Tie, Alyssa Ayala, Ning Zhou, Xiaofeng Qi
Nature, Published online: 29 January 2025; doi:10.1038/s41586-024-08484-9Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ-glutamyl carboxylase, which involves cholesterol and (...)

SARS-CoV-2 evolution on a dynamic immune landscape

mercredi 29 janvier 2025 par N. Alexia Raharinirina, Nils Gubela, Daniela Börnigen, Maureen Rebecca Smith, Djin-Ye Oh, Matthias Budt, Christin Mache, Claudia Schillings, Stephan Fuchs, Ralf Dürrwald, Thorsten Wolff, Martin Hölzer, Sofia Paraskevopoulou, Max von Kleist
Nature, Published online: 29 January 2025; doi:10.1038/s41586-024-08477-8A modelling approach predicts SARS-CoV-2 variant dynamics on the basis of immunity and cross-neutralization, which was shaped by a region’s SARS-CoV-2 infection (...)

Methanol transfer supports metabolic syntrophy between bacteria and archaea

mercredi 29 janvier 2025 par Yan Huang, Kensuke Igarashi, Laiyan Liu, Daisuke Mayumi, Tomomi Ujiie, Lin Fu, Min Yang, Yahai Lu, Lei Cheng, Souichiro Kato, Masaru K. Nobu
Nature, Published online: 29 January 2025; doi:10.1038/s41586-024-08491-wZhaonella formicivorans produces methanol, for a novel syntrophic interaction, without requiring methylated compounds as an input.

Molecular basis of vitamin K driven ?-carboxylation at membrane interface

mercredi 29 janvier 2025 par Qing Cao, Aaron Ammerman, Mierxiati Saimi, Zongtao Lin, Guomin Shen, Huaping Chen, Jie Sun, Mengqi Chai, Shixuan Liu, Fong-Fu Hsu, Andrzej M. Krezel, Michael L. Gross, Jinbin Xu, Benjamin A. Garcia, Bin Liu, Weikai Li
Nature, Published online: 29 January 2025; doi:10.1038/s41586-025-08648-1Molecular basis of vitamin K driven γ-carboxylation at membrane interface

How flight helped bats become invincible to viruses

mercredi 29 janvier 2025 par Ewen Callaway
Nature, Published online: 29 January 2025; doi:10.1038/d41586-025-00268-zThe mammals carry immune adaptations that emerged when their ancestors took to the skies.

Engineered heart muscle allografts for heart repair in primates and humans

mercredi 29 janvier 2025 par Ahmad-Fawad Jebran, Tim Seidler, Malte Tiburcy, Maria Daskalaki, Ingo Kutschka, Buntaro Fujita, Stephan Ensminger, Felix Bremmer, Amir Moussavi, Huaxiao Yang, Xulei Qin, Sophie Mißbach, Charis Drummer, Hassina Baraki, Susann Boretius, Christopher Hasenauer, Tobias Nette, Johannes Kowallick, Christian O. Ritter, Joachim Lotz, Michael Didié, Mathias Mietsch, Tim Meyer, George Kensah, Dennis Krüger, Md Sadman Sakib, Lalit Kaurani, Andre Fischer, Ralf Dressel, Ignacio Rodriguez-Polo, Michael Stauske, Sebastian Diecke, Kerstin Maetz-Rensing, Eva Gruber-Dujardin, Martina Bleyer, Beatrix Petersen, Christian Roos, Liye Zhang, Lutz Walter, Silke Kaulfuß, Gökhan Yigit, Bernd Wollnik, Elif Levent, Berit Roshani, Christiane Stahl-Henning, Philipp Ströbel, Tobias Legler, Joachim Riggert, Kristian Hellenkamp, Jens-Uwe Voigt, Gerd Hasenfuß, Rabea Hinkel, Joseph C. Wu, Rüdiger Behr, Wolfram-Hubertus Zimmermann
Nature, Published online: 29 January 2025; doi:10.1038/s41586-024-08463-0Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading to improved cardiac (...)

After boom

mercredi 29 janvier 2025 par Emma Burnett
Nature, Published online: 29 January 2025; doi:10.1038/d41586-025-00225-wKeeping it real.

‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases

mercredi 29 janvier 2025 par Ewen Callaway
Nature, Published online: 29 January 2025; doi:10.1038/d41586-025-00217-wThe human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.

Want to get a species protected? Publish in a small, niche journal

mercredi 29 janvier 2025 par Liam Drew
Nature, Published online: 29 January 2025; doi:10.1038/d41586-025-00144-wStudies are more likely to influence conservation law if they are published in specialist journals — but researchers worry that their true impact is being ignored in hiring and promotion (...)

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