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Cancer blood tests are everywhere. Do they really work?

mercredi 4 mars 2026 par Nic Fleming

Nature, Published online: 04 March 2026; doi:10.1038/d41586-026-00661-2Their makers claim they can detect dozens of cancer types — but some scientists say they could be missing many cancers or delivering the wrong diagnosis.

Nature

Skin cells boost distant antibody responses

mercredi 4 mars 2026 par Xueping Zhu, Caroline L. Sokol

Nature, Published online: 04 March 2026; doi:10.1038/d41586-026-00379-1How the skin enables immune defences is not fully clear. Now a pathway has been found in skin cells that boosts the production of antibodies to protect the whole (...)

Nature

Shared neural substrates of prosocial and parenting behaviours

mercredi 4 mars 2026 par Fangmiao Sun, Kayla Y. Lim, James Dang, Li I. Zhang, Ye Emily Wu, Weizhe Hong

Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10327-8Shared neural substrates of prosocial and parenting behaviours

Nature

Heart surgery with quick-setting magnetic fluid could prevent strokes

mercredi 4 mars 2026 par Nick Petri? Howe, Shamini Bundell

Nature, Published online: 04 March 2026; doi:10.1038/d41586-026-00742-2Injectable fluid safely fills area in which blood clots can form, in animal trials — plus, strong evidence that an elusive form of diamond has been made in the (...)

Nature

Magnetic gel injected into the heart could stop strokes

mercredi 4 mars 2026 par Nick Petri? Howe

Nature, Published online: 04 March 2026; doi:10.1038/d41586-026-00740-4The hydrogel-based plug blocks a part of the heart to cut stroke risk and was shown to be effective in rats and a pig.

Nature

Genome modelling and design across all domains of life with Evo 2

mercredi 4 mars 2026 par Garyk Brixi, Matthew G. Durrant, Jerome Ku, Mohsen Naghipourfar, Michael Poli, Gwanggyu Sun, Greg Brockman, Daniel Chang, Alison Fanton, Gabriel A. Gonzalez, Samuel H. King, David B. Li, Aditi T. Merchant, Eric Nguyen, Chiara Ricci-Tam, David W. Romero, Jonathan C. Schmok, Ali Taghibakhshi, Anton Vorontsov, Brandon Yang, Myra Deng, Liv Gorton, Nam Nguyen, Nicholas K. Wang, Michael T. Pearce, Elana Simon, Etowah Adams, Zachary J. Amador, Euan A. Ashley, Stephen A. Baccus, Haoyu Dai, Steven Dillmann, Stefano Ermon, Daniel Guo, Michael H. Herschl, Rajesh Ilango, Ken Janik, Amy X. Lu, Reshma Mehta, Mohammad R. K. Mofrad, Madelena Y. Ng, Jaspreet Pannu, Christopher Ré, John St. John, Jeremy Sullivan, Joseph Tey, Ben Viggiano, Kevin Zhu, Greg Zynda, Daniel Balsam, Patrick Collison, Anthony B. Costa, Tina Hernandez-Boussard, Eric Ho, Ming-Yu Liu, Thomas McGrath, Kimberly Powell, Sudarshan Pinglay, Dave P. Burke, Hani Goodarzi, Patrick D. Hsu, Brian L. Hie

Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10176-5Evo 2 is an artificial intelligence-based biological foundation model trained on 9 trillion DNA base pairs spanning all domains of life that predicts functional properties from genomic sequences and provides a rich (...)

Nature

DICER cleavage fidelity is governed by 5?-end binding pockets

mercredi 4 mars 2026 par Minh Khoa Ngo, Cong Truc Le, Tuan Anh Nguyen

Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10211-5Cryo-electron microscopy and massively parallel assays shed light on the mechanism by which DICER, a key enzyme in the RNase III family, cleaves RNA at precise locations to produce small (...)

Nature

Limited thermal tolerance in tropical insects and its genomic signature

mercredi 4 mars 2026 par Kim L. Holzmann, Thomas Schmitzer, Antonia Abels, Marko ?orkalo, Oliver Mitesser, Mareike Kortmann, Pedro Alonso-Alonso, Yenny Correa-Carmona, Andrea Pinos, Felipe Yon, Mabel Alvarado, Adrian Forsyth, Alejandro Lopera-Toro, Gunnar Brehm, Alexander Keller, Mark Otieno, Ingolf Steffan-Dewenter, Marcell K. Peters

Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10155-wA survey of tropical insect populations and thermal tolerance limits indicates that species from lowland areas have low capacity to survive increased temperatures, and that thermal tolerance is limited by fundamental (...)

Nature

Long-term thrombus-free left atrial appendage occlusion via magnetofluids

mercredi 4 mars 2026 par Shu Wang, Wenhao Ju, Donglin Zhuang, Zhecheng Chen, Dongliang Zhao, Shunyuan Huang, Tiankuo Wang, Mingxue Cai, Siyu Liu, Shixiong Fu, Zhiguo Cheng, Wenchang Tan, Xiangbin Pan, Xinyu Wu, Shouzheng Wang, Tiantian Xu

Nature, Published online: 04 March 2026; doi:10.1038/s41586-025-10091-1In the presence of a sufficient magnetic field, magnetofluids can resist high-speed blood flow, offering a personalized and complete strategy for left atrial appendage (...)

Nature

A metabolic alarmin from keratinocytes potentiates systemic humoral immunity

mercredi 4 mars 2026 par Zhenglin Ji, Ji Gao, Shaocun Zhang, Jiajie Li, Haijing Wu, Jing Yao, Xianqiang Ma, Yue Xin, Yongjie Zhu, Meng Zhao, Zhidan Zhao, Kai Shen, Tao Wu, Xinmin Qian, Juanjuan Wang, Haoran An, Yuxin Li, Wenbo Sun, Qiancheng Zhao, Xiaoying Zhou, Ruiyu Gao, Qinghui Duan, Cuifeng Li, Xiaoke Geng, Ming Yang, Rong Xiao, Juan Liu, Wang Wang, Ji Wang, Yesheng Fu, Jing-Ren Zhang, Xiangjun Chen, Pei Tong, Gong Cheng, Hai Qi, Li Wu, Wenwen Zeng, Qiaoran Xi, Lingqiang Zhang, Yuping Lai, Wei Yang, Yonghui Zhang, Qianjin Lu, Wanli Liu

Nature, Published online: 04 March 2026; doi:10.1038/s41586-026-10167-6Farnesyl pyrophosphate—a mevalonate pathway metabolic intermediate—is an endogenous alarmin that enhances IgG antibody responses through keratinocyte-derived IL-6 and (...)

Nature