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Non-Abelian lattice gauge fields in photonic synthetic frequency dimensions

mercredi 1er janvier 2025 par Dali Cheng, Kai Wang, Charles Roques-Carmes, Eran Lustig, Olivia Y. Long, Heming Wang, Shanhui Fan

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08259-2Non-Abelian lattice gauge fields in photonic synthetic frequency dimensions can be used to study lattice physics in a scalable and programmable way.

Nature

Formation of individual stripes in a mixed-dimensional cold-atom Fermi–Hubbard system

mercredi 1er janvier 2025 par Dominik Bourgund, Thomas Chalopin, Petar Bojovi?, Henning Schlömer, Si Wang, Titus Franz, Sarah Hirthe, Annabelle Bohrdt, Fabian Grusdt, Immanuel Bloch, Timon A. Hilker

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08270-7Observations of the formation of individual stripes in a mixed-dimensional cold-atom Fermi–Hubbard quantum simulator are described, enhancing understanding of the phase diagram of high-temperature superconducting materials (...)

Nature

Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice

mercredi 1er janvier 2025 par Kelly Jin, Zizhen Yao, Cindy T. J. van Velthoven, Eitan S. Kaplan, Katie Glattfelder, Samuel T. Barlow, Gabriella Boyer, Daniel Carey, Tamara Casper, Anish Bhaswanth Chakka, Rushil Chakrabarty, Michael Clark, Max Departee, Marie Desierto, Amanda Gary, Jessica Gloe, Jeff Goldy, Nathan Guilford, Junitta Guzman, Daniel Hirschstein, Changkyu Lee, Elizabeth Liang, Trangthanh Pham, Melissa Reding, Kara Ronellenfitch, Augustin Ruiz, Josh Sevigny, Nadiya Shapovalova, Lyudmila Shulga, Josef Sulc, Amy Torkelson, Herman Tung, Boaz Levi, Susan M. Sunkin, Nick Dee, Luke Esposito, Kimberly A. Smith, Bosiljka Tasic, Hongkui Zeng

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08350-8A comprehensive single-cell RNA sequencing study delineates cell-type-specific transcriptomic changes in the brain associated with normal ageing that will inform the investigation into functional changes and the (...)

Nature

Monoallelic expression can govern penetrance of inborn errors of immunity

mercredi 1er janvier 2025 par O’Jay Stewart, Conor Gruber, Haley E. Randolph, Roosheel Patel, Meredith Ramba, Enrica Calzoni, Lei Haley Huang, Jay Levy, Sofija Buta, Angelica Lee, Christos Sazeides, Zoe Prue, David P. Hoytema van Konijnenburg, Ivan K. Chinn, Luis A. Pedroza, James R. Lupski, Erica G. Schmitt, Megan A. Cooper, Anne Puel, Xiao Peng, Stéphanie Boisson-Dupuis, Jacinta Bustamante, Satoshi Okada, Marta Martin-Fernandez, Jordan S. Orange, Jean-Laurent Casanova, Joshua D. Milner, Dusan Bogunovic

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08346-4Somatically determined preferential allelic expression of select genes that when mutated cause inborn errors of immunity corresponds with disease phenotypes, suggesting that the penetrance and expressivity of monogenic (...)

Nature

Infrared nanosensors of piconewton to micronewton forces

mercredi 1er janvier 2025 par Natalie Fardian-Melamed, Artiom Skripka, Benedikt Ursprung, Changhwan Lee, Thomas P. Darlington, Ayelet Teitelboim, Xiao Qi, Maoji Wang, Jordan M. Gerton, Bruce E. Cohen, Emory M. Chan, P. James Schuck

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08221-2An avalanching-nanoparticle force sensor that can operate in the piconewton-to-micronewton range with exceptional force responsiveness is achieved by using the mechanical sensitivity of the photon-avalanching (...)

Nature

Dysregulation of mTOR signalling is a converging mechanism in lissencephaly

mercredi 1er janvier 2025 par Ce Zhang, Dan Liang, A. Gulhan Ercan-Sencicek, Aybike S. Bulut, Joelly Cortes, Iris Q. Cheng, Octavian Henegariu, Sayoko Nishimura, Xinyuan Wang, A. Buket Peksen, Yutaka Takeo, Caner Caglar, TuKiet T. Lam, Merve Nur Koroglu, Anand Narayanan, Francesc Lopez-Giraldez, Danielle F. Miyagishima, Ketu Mishra-Gorur, Tanyeri Barak, Katsuhito Yasuno, E. Zeynep Erson-Omay, Cengiz Yalcinkaya, Guilin Wang, Shrikant Mane, Hande Kaymakcalan, Aslan Guzel, A. Okay Caglayan, Beyhan Tuysuz, Nenad Sestan, Murat Gunel, Angeliki Louvi, Kaya Bilguvar

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08341-9Cellular, transcriptomic and proteomic analyses of organoids derived from human induced pluripotent stem cells show that mTOR pathway hypoactivation is involved in two genetically distinct lissencephaly spectrum (...)

Nature

Diversity and biogeography of the bacterial microbiome in glacier-fed streams

mercredi 1er janvier 2025 par Leïla Ezzat, Hannes Peter, Massimo Bourquin, Susheel Bhanu Busi, Grégoire Michoud, Stilianos Fodelianakis, Tyler J. Kohler, Thomas Lamy, Aileen Geers, Paraskevi Pramateftaki, Florian Baier, Ramona Marasco, Daniele Daffonchio, Nicola Deluigi, Paul Wilmes, Michail Styllas, Martina Schön, Matteo Tolosano, Vincent De Staercke, Tom J. Battin

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08313-zLeveraging metabarcoding and metagenomics, a survey of bacteria in the benthic microbiome across 152 glacier-fed streams (GFSs) provides a global reference for future climate-change microbiology studies on the vanishing GFS (...)

Nature

Magnetospheric origin of a fast radio burst constrained using scintillation

mercredi 1er janvier 2025 par Kenzie Nimmo, Ziggy Pleunis, Paz Beniamini, Pawan Kumar, Adam E. Lanman, D. Z. Li, Robert Main, Mawson W. Sammons, Shion Andrew, Mohit Bhardwaj, Shami Chatterjee, Alice P. Curtin, Emmanuel Fonseca, B. M. Gaensler, Ronniy C. Joseph, Zarif Kader, Victoria M. Kaspi, Mattias Lazda, Calvin Leung, Kiyoshi W. Masui, Ryan Mckinven, Daniele Michilli, Ayush Pandhi, Aaron B. Pearlman, Masoud Rafiei-Ravandi, Ketan R. Sand, Kaitlyn Shin, Kendrick Smith, Ingrid H. Stairs

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08297-wThe detection of scintillation caused by inhomogeneous plasma near a fast radio burst indicates an emission process that occurs within or just beyond the magnetosphere of a compact (...)

Nature

Structural diversity of axonemes across mammalian motile cilia

mercredi 1er janvier 2025 par Miguel Ricardo Leung, Chen Sun, Jianwei Zeng, Jacob R. Anderson, Qingwei Niu, Wei Huang, Willem E. M. Noteborn, Alan Brown, Tzviya Zeev-Ben-Mordehai, Rui Zhang

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08337-5Cryoelectron microscopy, cryoelectron tomography and proteomics are used to resolve the 96-nm modular repeat of axonemal doublet microtubules from both sperm flagella and epithelial cilia of the oviduct, brain ventricles (...)

Nature

Gliomagenesis mimics an injury response orchestrated by neural crest-like cells

mercredi 1er janvier 2025 par Akram A. Hamed, Kui Hua, Quang M. Trinh, Benjamin D. Simons, John C. Marioni, Lincoln D. Stein, Peter B. Dirks

Nature, Published online: 01 January 2025; doi:10.1038/s41586-024-08356-2A study using glioblastoma mouse models, serial magnetic resonance imaging and single-cell profiling details changes in the identity and balance of cellular states from initiation of tumorigenesis to the end (...)

Nature