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Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes

mercredi 27 octobre 2021 par Omer Keinan, Joseph M. Valentine, Haopeng Xiao, Sushil K. Mahata, Shannon M. Reilly, Mohammad Abu-Odeh, Julia H. Deluca, Benyamin Dadpey, Leslie Cho, Austin Pan, Ruth T. Yu, Yang Dai, Christopher Liddle, Michael Downes, Ronald M. Evans, Aldons J. Lusis, Markku Laakso, Edward T. Chouchani, Mikael Ryde’n, Alan R. Saltiel
Nature, Published online: 27 October 2021; doi:10.1038/s41586-021-04019-8Increased glycogen metabolism in adipocytes leads to expression of uncoupling protein 1, thereby linking glucose metabolism to thermogenesis.

Fossil evidence unveils an early Cambrian origin for Bryozoa

mercredi 27 octobre 2021 par Zhiliang Zhang, Zhifei Zhang, Junye Ma, Paul D. Taylor, Luke C. Strotz, Sarah M. Jacquet, Christian B. Skovsted, Feiyang Chen, Jian Han, Glenn A. Brock
Nature, Published online: 27 October 2021; doi:10.1038/s41586-021-04033-wInterpretation of the early Cambrian fossil Protomelission gatehousei9 as a potential stem-group bryozoan realigns the fossil record with molecular clock estimations of the origins of (...)

Wolbachia goes to work in the war on mosquitoes

mercredi 27 octobre 2021 par Sandy Ong
Nature, Published online: 27 October 2021; doi:10.1038/d41586-021-02914-8The bacterium has helped combat dengue, but can it be used to purge other mosquito-borne diseases?

Bryozoan fossils found at last in deposits from the Cambrian period

mercredi 27 octobre 2021 par Andrej Ernst, Mark A. Wilson
Nature, Published online: 27 October 2021; doi:10.1038/d41586-021-02874-zMolecular evidence has long indicated that aquatic animals called bryozoans should be found among the fossils of the Cambrian period, around 541 million years ago. Yet they have been conspicuously absent, until (...)

The advocacy frontier

mercredi 27 octobre 2021 par Liam Drew
Nature, Published online: 27 October 2021; doi:10.1038/d41586-021-02926-4Several major organizations are calling for radical reforms to improve oral health. What’s holding them up?

The genomic origins of the Bronze Age Tarim Basin mummies

mercredi 27 octobre 2021 par Fan Zhang, Chao Ning, Ashley Scott, Qiaomei Fu, Rasmus Bjørn, Wenying Li, Dong Wei, Wenjun Wang, Linyuan Fan, Idilisi Abuduresule, Xingjun Hu, Qiurong Ruan, Alipujiang Niyazi, Guanghui Dong, Peng Cao, Feng Liu, Qingyan Dai, Xiaotian Feng, Ruowei Yang, Zihua Tang, Pengcheng Ma, Chunxiang Li, Shizhu Gao, Yang Xu, Sihao Wu, Shaoqing Wen, Hong Zhu, Hui Zhou, Martine Robbeets, Vikas Kumar, Johannes Krause, Christina Warinner, Choongwon Jeong, Yinqiu Cui
Nature, Published online: 27 October 2021; doi:10.1038/s41586-021-04052-7A genomic analysis of human remains from the Bronze Age provides insights into the origin of the Tarim Basin mummies from the Xinjiang region.

Indo-Pacific Walker circulation drove Pleistocene African aridification

mercredi 27 octobre 2021 par H. J. L. van der Lubbe, I. R. Hall, S. Barker, S. R. Hemming, T. F. Baars, A. Starr, J. Just, B. C. Backeberg, J. C. A. Joordens
Nature, Published online: 27 October 2021; doi:10.1038/s41586-021-03896-3A record of flow-speed variations from an ocean core shows that a key component of Indian Ocean circulation rapidly accelerated 2.1 million years ago, coincident with intensification of Pacific Walker (...)

The orbitofrontal cortex maps future navigational goals

mercredi 27 octobre 2021 par Raunak Basu, Robert Gebauer, Tim Herfurth, Simon Kolb, Zahra Golipour, Tatjana Tchumatchenko, Hiroshi T. Ito
Nature, Published online: 27 October 2021; doi:10.1038/s41586-021-04042-9Dedicated cells in the hippocampus and entorhinal cortex map an animal s instantaneous position in space; by contrast, its future goal location is represented in the orbitofrontal cortex, a structure within the broader (...)

TMK-based cell-surface auxin signalling activates cell-wall acidification

mercredi 27 octobre 2021 par Wenwei Lin, Xiang Zhou, Wenxin Tang, Koji Takahashi, Xue Pan, Jiawei Dai, Hong Ren, Xiaoyue Zhu, Songqin Pan, Haiyan Zheng, William M. Gray, Tongda Xu, Toshinori Kinoshita, Zhenbiao Yang
Nature, Published online: 27 October 2021; doi:10.1038/s41586-021-03976-4Auxin induces transmembrane-kinase-dependent activation of H+-ATPase in the plasma membrane through phosphorylation of its penultimate threonine residue, promoting apoplastic acidification and hypocotyl cell elongation in (...)

A solar C/O and sub-solar metallicity in a hot Jupiter atmosphere

mercredi 27 octobre 2021 par Michael R. Line, Matteo Brogi, Jacob L. Bean, Siddharth Gandhi, Joseph Zalesky, Vivien Parmentier, Peter Smith, Gregory N. Mace, Megan Mansfield, Eliza M.-R. Kempton, Jonathan J. Fortney, Evgenya Shkolnik, Jennifer Patience, Emily Rauscher, Jean-Michel Désert, Joost P. Wardenier
Nature, Published online: 27 October 2021; doi:10.1038/s41586-021-03912-6The C/O ratio of the transiting hot Jupiter WASP-77Ab is measured here and found to be approximately solar, though the (C+O)/H ratio is subsolar.

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