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A licence to kill during inflammation

mercredi 12 juin 2019 par Kengo Nozaki, Edward A. Miao
Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01764-9Inflammasomes are protein complexes that fight infection by driving inflammation or cell death. It now seems that the protein NEK7 provides a ‘licence’ for the formation of inflammasomes containing the protein (...)

How 11 experts spent 2 days trying to find consensus on climate and conflict

mercredi 12 juin 2019
Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01830-2Expert elicitation draws on diverse specialists to synthesize conflicting views and evidence.

Daily briefing: An X-ray map of the Universe

mercredi 12 juin 2019 par Flora Graham
Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01875-3Space telescope marks a “return to world-class science” for Russia, mouse lemurs might be the next big thing in genetics and an open-access publishing model in which journals compete for (...)

Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis

mercredi 12 juin 2019 par Ting Su, Toshiaki Izawa, Matthias Thoms, Yui Yamashita, Jingdong Cheng, Otto Berninghausen, F. Ulrich Hartl, Toshifumi Inada, Walter Neupert, Roland Beckmann
Nature, Published online: 12 June 2019; doi:10.1038/s41586-019-1307-zCryo-electron microscopy structures of the yeast 60S ribosomal subunit in complex with Vms1 provides insights into the roles of proteins in the ribosome-associated quality control (...)

Ozone mystery laid to rest

mercredi 12 juin 2019 par Mathew Evans
Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01752-zMeasurements of atmospheric ozone levels taken during the nineteenth century cast doubt on the computational models used today to simulate the atmosphere. An independent proxy of past ozone levels offers (...)

Atypical behaviour and connectivity in SHANK3-mutant macaques

mercredi 12 juin 2019 par Yang Zhou, Jitendra Sharma, Qiong Ke, Rogier Landman, Jingli Yuan, Hong Chen, David S. Hayden, John W. Fisher III, Minqing Jiang, William Menegas, Tomomi Aida, Ting Yan, Ying Zou, Dongdong Xu, Shivangi Parmar, Julia B. Hyman, Adrian Fanucci-Kiss, Olivia Meisner, Dongqing Wang, Yan Huang, Yaqing Li, Yanyang Bai, Wenjing Ji, Xinqiang Lai, Weiqiang Li, Lihua Huang, Zhonghua Lu, Liping Wang, Sheeba A. Anteraper, Mriganka Sur, Huihui Zhou, Andy Peng Xiang, Robert Desimone, Guoping Feng, Shihua Yang
Nature, Published online: 12 June 2019; doi:10.1038/s41586-019-1278-0The CRISPR–Cas9-mediated generation of germline-transmissible mutations of SHANK3 in cynomolgus macaques (Macaca fascicularis) forms the basis of a non-human-primate model of autism spectrum disorder and Phelan–McDermid (...)

Atypical behaviour and connectivity in SHANK3-mutant macaques

mercredi 12 juin 2019 par Yang Zhou, Jitendra Sharma, Qiong Ke, Rogier Landman, Jingli Yuan, Hong Chen, David S. Hayden, John W. Fisher III, Minqing Jiang, William Menegas, Tomomi Aida, Ting Yan, Ying Zou, Dongdong Xu, Shivangi Parmar, Julia B. Hyman, Adrian Fanucci-Kiss, Olivia Meisner, Dongqing Wang, Yan Huang, Yaqing Li, Yanyang Bai, Wenjing Ji, Xinqiang Lai, Weiqiang Li, Lihua Huang, Zhonghua Lu, Liping Wang, Sheeba A. Anteraper, Mriganka Sur, Huihui Zhou, Andy Peng Xiang, Robert Desimone, Guoping Feng, Shihua Yang
Nature, Published online: 12 June 2019; doi:10.1038/s41586-019-1278-0The CRISPR–Cas9-mediated generation of germline-transmissible mutations of SHANK3 in cynomolgus macaques (Macaca fascicularis) forms the basis of a non-human-primate model of autism spectrum disorder and Phelan–McDermid (...)

How nanostructures create the hues of the earliest photos

mercredi 12 juin 2019
Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01839-7Microscopic particles give daguerreotypes a reddish cast when viewed from certain angles.

This artificial island was built by farmers more than five millennia ago

mercredi 12 juin 2019
Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01814-2Rocky outposts are much older than previously supposed and might have served ritual purposes.

Tiny flying saucers are actually odd new microbes

mercredi 12 juin 2019
Nature, Published online: 12 June 2019; doi:10.1038/d41586-019-01827-xSingle-celled life forms display original movement style.

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