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Conformation of sister chromatids in the replicated human genome

mercredi 23 septembre 2020 par Michael Mitter, Catherina Gasser, Zsuzsanna Takacs, Christoph C. H. Langer, Wen Tang, Gregor Jessberger, Charlie T. Beales, Eva Neuner, Stefan L. Ameres, Jan-Michael Peters, Anton Goloborodko, Ronald Micura, Daniel W. Gerlich
Nature, Published online: 23 September 2020; doi:10.1038/s41586-020-2744-4Modified chromosome conformation capture (Hi-C) technology is used to characterize the interactions between sister chromatids, despite their identical DNA (...)

Colloidal diamond

mercredi 23 septembre 2020 par Mingxin He, Johnathon P. Gales, Étienne Ducrot, Zhe Gong, Gi-Ra Yi, Stefano Sacanna, David J. Pine
Nature, Published online: 23 September 2020; doi:10.1038/s41586-020-2718-6Self-assembly of cubic diamond crystals is demonstrated, by using precursor clusters of particles with carefully placed ‘sticky’ patches that attract and bind adjacent clusters in specific (...)

The first-ever image of a black hole is now a movie

mercredi 23 septembre 2020 par Davide Castelvecchi
Nature, Published online: 23 September 2020; doi:10.1038/d41586-020-02717-3Pictures created from old observations show the void’s stormy evolution over the past decade.

Making radiation oncology more personal

mercredi 23 septembre 2020 par Amanda B. Keener
Nature, Published online: 23 September 2020; doi:10.1038/d41586-020-02677-8The technology to fine-tune radiotherapy to an individual is here, but a lack of research is holding back its use.

Hippocampal CA2 sharp-wave ripples reactivate and promote social memory

mercredi 23 septembre 2020 par Azahara Oliva, Antonio Fernández-Ruiz, Felix Leroy, Steven A. Siegelbaum
Nature, Published online: 23 September 2020; doi:10.1038/s41586-020-2758-ySocial memory is consolidated in the brain through the reactivation of neuronal firing by sharp-wave ripples in the CA2 region of the hippocampus, in a similar way to the consolidation of spatial (...)

After decades of trying, scientists coax plastic particles into a diamond-like structure

mercredi 23 septembre 2020 par Benjamin Thompson, Nick Howe
Nature, Published online: 23 September 2020; doi:10.1038/d41586-020-02722-6Coaxing tiny colloid particles into a diamond structure, and manipulating cell death and homeostasis in neurodegenerative disease.

The hysteresis of the Antarctic Ice Sheet

mercredi 23 septembre 2020 par Julius Garbe, Torsten Albrecht, Anders Levermann, Jonathan F. Donges, Ricarda Winkelmann
Nature, Published online: 23 September 2020; doi:10.1038/s41586-020-2727-5Modelling shows that the Antarctic Ice Sheet exhibits multiple temperature thresholds beyond which ice loss would become irreversible, and once melted, the ice sheet can regain its previous mass only if the climate cools (...)

Elusive photonic crystals come a step closer

mercredi 23 septembre 2020 par John C. Crocker
Nature, Published online: 23 September 2020; doi:10.1038/d41586-020-02656-zResearchers have long sought materials in which light behaves the way electrons do in semiconductors. A workable approach for growing such materials in bulk now seems at hand, and could lead to advances in (...)

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

mercredi 23 septembre 2020 par Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature, Published online: 23 September 2020; doi:10.1038/s41586-020-2746-2Genome-wide CRISPR screens in mouse cancer cell lines are used to identify a core, conserved set of genes and pathways that govern how cancer cells evade killing by cytotoxic T (...)

Mapping carbon accumulation potential from global natural forest regrowth

mercredi 23 septembre 2020 par Susan C. Cook-Patton, Sara M. Leavitt, David Gibbs, Nancy L. Harris, Kristine Lister, Kristina J. Anderson-Teixeira, Russell D. Briggs, Robin L. Chazdon, Thomas W. Crowther, Peter W. Ellis, Heather P. Griscom, Valentine Herrmann, Karen D. Holl, Richard A. Houghton, Cecilia Larrosa, Guy Lomax, Richard Lucas, Palle Madsen, Yadvinder Malhi, Alain Paquette, John D. Parker, Keryn Paul, Devin Routh, Stephen Roxburgh, Sassan Saatchi, Johan van den Hoogen, Wayne S. Walker, Charlotte E. Wheeler, Stephen A. Wood, Liang Xu, Bronson W. Griscom
Nature, Published online: 23 September 2020; doi:10.1038/s41586-020-2686-xA one-kilometre-resolution map of aboveground carbon accumulation rates of forest regrowth shows 100-fold variation across the globe, with rates 32% higher on average than IPCC (...)

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