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A secreted endosymbiont protein essential for colonizing host cells

mercredi 1er juillet 2026 par Gerald P. Maeda, Allen Z. Xue, Ethan W. Yu, Aadhunik Sundar, Derrick L. Kamp, J. Elijah Powell, Thomas E. Smith, Nancy A. Moran

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10711-4SyeA was present in the Buchnera ancestor, is secreted into the host cytoplasm, is homologous to secreted effectors of bacterial pathogens and is essential for Buchnera (...)

Nature

Replication-stress-induced chromatin loops protect fork stability

mercredi 1er juillet 2026 par Vincent Gaggioli, Kaustav Sengupta, Ashutosh Choudhury, Joanna Paulson, Raviprasad Kuthethur, Collin Bakker, Jialun Li, Calvin S. Y. Lo, Alex Whale, Jeroen van den Berg, Leire Asua Intxausti, Noelia Gil-Lanza, Iván Galván-Femenía, Eleni Maria Manolika, Sangavi Eswaran, Hina N. Khan, Estel Ferré, Gregorie Stik, Alexander van Oudenaarden, Argyris Papantonis, Jonathan Houseley, Sriram Sridharan, Arnab Ray Chaudhuri, Aleix Bayona-Feliu, Nitika Taneja

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10695-1Replication stress induces the formation of transient chromatin loops that enclose de novo heterochromatin-enriched stalled replication forks.

Nature

Isomeric multi-hydrogen-bonding enables blue perovskite LEDs

mercredi 1er juillet 2026 par Yuanzhi Wang, Chengxi Zhang, Yingguo Yang, Lingmei Kong, Bin Zhao, Zirui Liu, Pu Du, Dongyuan Han, Mengjia Cen, Lin Wang, Sheng Wang, Yanjun Liu, Lyudmila Turyanska, Andrew Bruhacs, Ning Wang, Xuyong Yang

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10723-0Hydrogen-bonding networks engineered with isomeric molecules enable stable, saturated blue perovskite LEDs with record external quantum efficiencies up to 22.0%, advancing high-performance full-colour display (...)

Nature

Towards the construction of a virtual yeast

mercredi 1er juillet 2026 par Liujia Qian, Zizhuo Zhou, Peijie Zhou, Zhen Dong, Xudong Zhang, Zhenwu Dai, Zhangyang Gao, Siqi Sun, Kevin R. Roy, Shuaiyao Wang, Nicola Zamboni, Charles Boone, Michael Costanzo, Jianzhe Li, Gianni Liti, Jia-Xing Yue, Markus Ralser, Evan Williams, Mattia Zampieri, Heng Jiang, Tailin Wu, Yalin Wang, Feiran Li, Joseph Schacherer, Rui Sun, Zhaoxing Li, Yaming Deng, Yi Chen, Zhiping Xie, Huiqiang Lou, Xiaowen Wang, Linhai Xie, Han Wen, Liangyi Chen, Kai Lei, George Rosenberger, Xue Cai, Yingrui Wang, Qi Xiao, Huaizong Shen, Gaowen Liu, Lei Ma, Brenda Andrews, Hui Lu, Kiryl Piatkevich, Yi Zhu, Lei Bai, Yizhi Cai, Yuping Chen, Weinan E, Ge Gao, Fuchu He, Luonan Chen, Stan Z. Li, Hongwu Ma, Liang Qiao, Lars M. Steinmetz, Leihan Tang, Tang Tang, Xiaofan Zhang, Jing Yang, Yifan Yang, Kaicheng Yu, Jianyang Zeng, Yefeng Zheng, Bowen Zhou, Tiannan Guo

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10574-9A virtual yeast, an artificial intelligence-driven agent for modelling eukaryotic cellular behaviours, is described.

Nature

Togetherness: How cooperation built the world

mercredi 1er juillet 2026 par Benjamin Thompson

Nature, Published online: 01 July 2026; doi:10.1038/d41586-026-02067-6Science journalist Rowan Hooper joins us to talk about symbiosis and the importance of organisms working together.

Nature

Backreaction of stimulated Hawking radiation in an optical analogue

mercredi 1er juillet 2026 par Lorenzo M. Procopio, Raul Aguero-Santacruz, David Bermudez, Ulf Leonhardt

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10720-3By using a fibre-optical analogue of the physics of black holes, theoretical and experimental evidence is presented for the process underpinning the generation of Hawking radiation and its backreaction onto the optical (...)

Nature

Harmonizing standards and resources for the medical genome

mercredi 1er juillet 2026 par Euan A. Ashley, Ash A. Alizadeh, Hanae Armitage, Ami S. Bhatt, Yair Blumenfeld, Andrew Carroll, R. Martin Chavez, Petros Giannikopoulos, Megan E. Grove, Meghan C. Halley, Kiran Khush, Niall J. Lennon, Samantha Maragh, Alexander Marson, Benedict Paten, Adam M. Phillippy, Matthew H. Porteus, Heidi L. Rehm, Bradley R. Ringeisen, Julia Salzman, Valerie A. Schneider, Fritz J. Sedlazeck, Lars M. Steinmetz, Fyodor D. Urnov, Stacia K. Wyman, Justin M. Zook, Lloyd B. Minor, Jennifer A. Doudna

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10621-5This Perspective examines the challenges and opportunities of genomic sequencing across multiple clinical applications, including genetic therapies, and calls for the establishment of new, centralized reference standards to (...)

Nature

Daily briefing: How to brew a climate-friendly coffee

mardi 30 juin 2026 par Flora Graham

Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-02076-5Researchers are racing to safeguard coffee from climate change. Plus, how ticks are making people allergic to meat and how AI tools can help neurodivergent students succeed in their science (...)

Nature

Coffee is under threat: how scientists are fighting to save it from extinction

mardi 30 juin 2026 par Davide Castelvecchi

Nature, Published online: 30 June 2026; doi:10.1038/d41586-026-01965-zCoffee plants are critically endangered by climate change. Researchers are finding solutions to keep scientists supplied with their favourite discovery fuel.

Nature

Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies

mardi 30 juin 2026 par Lorie Marchitto, Kshitij Wagh, Ryan S. Roark, Severin Coleon, Hui Li, Ashwin N. Skelly, Michael P. Hogarty, Rumi Habib, Wenge Ding, Kasirajan Ayyanathan, Weimin Liu, Zizhang Sheng, Yicheng Guo, Joena Bal, Lena M. Smith, Laura L. Sutherland, Younghoon Park, Andrew J. Connell, Frederic Bibollet-Ruche, Emily Lewis, Samantha J. Plante, Macy J. Akeley, Jinery Lora, Chengyan Zhao, John W. Carey, Christian L. Martella, Yingying Li, Mary S. Campion, Melinda G. Lituchy, Rebecca A. Osbaldeston, Colette G. Gordon, Amie Albertus, Justin Su, Chiaki Noguchi, Ying K. Tam, Christopher Barbosa, Bo Liang, Khaled Amereh, Xuduo Li, Agnes A. Walsh, Darrell J. Irvine, Raiees Andrabi, Robert J. Edwards, Edward F. Kreider, Drew Weissman, Lawrence Shapiro, Peter D. Kwong, Bette T. Korber, Barton F. Haynes, Kevin O. Saunders, Beatrice H. Hahn, George M. Shaw

Nature, Published online: 30 June 2026; doi:10.1038/s41586-026-10838-4Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies

Nature