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Multiple sclerosis enters a grey area

mercredi 20 février 2019 par Jenna L. Pappalardo, David A. Hafler
Multiple sclerosis enters a grey area Multiple sclerosis enters a grey area, Published online: 20 February 2019; doi:10.1038/d41586-019-00563-6Studies of multiple sclerosis have long focused on the white matter of the brain. Insights into how immune cells target the brain’s grey matter now (...)

A single-cell molecular map of mouse gastrulation and early organogenesis

mercredi 20 février 2019 par Blanca Pijuan-Sala, Jonathan A. Griffiths, Carolina Guibentif, Tom W. Hiscock, Wajid Jawaid, Fernando J. Calero-Nieto, Carla Mulas, Ximena Ibarra-Soria, Richard C. V. Tyser, Debbie Lee Lian Ho, Wolf Reik, Shankar Srinivas, Benjamin D. Simons, Jennifer Nichols, John C. Marioni, Berthold Göttgens
A single-cell molecular map of mouse gastrulation and early organogenesis A single-cell molecular map of mouse gastrulation and early organogenesis, Published online: 20 February 2019; doi:10.1038/s41586-019-0933-9Single-cell profiling is used to create a molecular-level atlas of cell (...)

β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration

mercredi 20 février 2019 par Dmitri Lodygin, Moritz Hermann, Nils Schweingruber, Cassandra Flügel-Koch, Takashi Watanabe, Corinna Schlosser, Arianna Merlini, Henrike Körner, Hsin-Fang Chang, Henrike J. Fischer, Holger M. Reichardt, Marta Zagrebelsky, Brit Mollenhauer, Sebastian Kügler, Dirk Fitzner, Jens Frahm, Christine Stadelmann, Michael Haberl, Francesca Odoardi, Alexander Flügel
β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration, Published online: 20 February 2019; doi:10.1038/s41586-019-0964-2In a rat model of multiple sclerosis, β-synuclein-specific T cells induce (...)

Neuromodulatory control of localized dendritic spiking in critical period cortex

mercredi 20 février 2019 par Courtney E. Yaeger, Dario L. Ringach, Joshua T. Trachtenberg
Neuromodulatory control of localized dendritic spiking in critical period cortex Neuromodulatory control of localized dendritic spiking in critical period cortex, Published online: 20 February 2019; doi:10.1038/s41586-019-0963-3A transient circuit that links cholinergic neuromodulation and (...)

Why neutrons and protons are modified inside nuclei

mercredi 20 février 2019 par Gerald Feldman
Why neutrons and protons are modified inside nuclei Why neutrons and protons are modified inside nuclei, Published online: 20 February 2019; doi:10.1038/d41586-019-00577-0The structure of a neutron or a proton is modified when the particle is bound in an atomic nucleus. Experimental data (...)

The seventh inner moon of Neptune

mercredi 20 février 2019 par M. R. Showalter, I. de Pater, J. J. Lissauer, R. S. French
The seventh inner moon of Neptune The seventh inner moon of Neptune, Published online: 20 February 2019; doi:10.1038/s41586-019-0909-9Hubble Space Telescope observations of the seventh inner moon of Neptune, Hippocamp, show that it is smaller than the other six, orbits near Proteus and probably (...)

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

mercredi 20 février 2019 par Aaron T. Whiteley, James B. Eaglesham, Carina C. de Oliveira Mann, Benjamin R. Morehouse, Brianna Lowey, Eric A. Nieminen, Olga Danilchanka, David S. King, Amy S. Y. Lee, John J. Mekalanos, Philip J. Kranzusch
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals Bacterial cGAS-like enzymes synthesize diverse nucleotide signals, Published online: 20 February 2019; doi:10.1038/s41586-019-0953-5A bacterial family of cGAS/DncV-like nucleotidyltransferases synthesizes a diverse range of (...)

Classify viruses — the gain is worth the pain

mercredi 20 février 2019 par Jens H. Kuhn, Yuri I. Wolf, Mart Krupovic, Yong-Zhen Zhang, Piet Maes, Valerian V. Dolja, Eugene V. Koonin
Classify viruses — the gain is worth the pain Classify viruses — the gain is worth the pain, Published online: 20 February 2019; doi:10.1038/d41586-019-00599-8Viruses hold solutions to a lot of problems, so let’s fund and reward cataloguing, urge Jens H. Kuhn and (...)

Gene-edited animal creators look beyond US market

mercredi 20 février 2019 par Heidi Ledford
Gene-edited animal creators look beyond US market Gene-edited animal creators look beyond US market, Published online: 20 February 2019; doi:10.1038/d41586-019-00600-4Tired of regulatory confusion and a lack of funding, some US researchers are taking their gene-edited livestock (...)

Daily briefing: Israel is sending the first privately built lander to the Moon

mercredi 20 février 2019 par Flora Graham
Daily briefing: Israel is sending the first privately built lander to the Moon Daily briefing: Israel is sending the first privately built lander to the Moon, Published online: 20 February 2019; doi:10.1038/d41586-019-00652-6A new era of lunar exploration, the first leader of the Nigeria Centre (...)

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