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Deploy diverse renewables to save tropical rivers

mercredi 15 mai 2019 par Rafael J. P. Schmitt, Noah Kittner, G. Mathias Kondolf, Daniel M. Kammen
Nature, Published online: 15 May 2019; doi:10.1038/d41586-019-01498-8A strategic mix of solar, wind and storage technologies around river basins would be safer and cheaper than building large dams, argue Rafael J. P. Schmitt, Noah Kittner and (...)

Chinese investments fuel growth in African science

mercredi 15 mai 2019 par Antoaneta Roussi
Nature, Published online: 15 May 2019; doi:10.1038/d41586-019-01398-xAfrica has emerged as a major partner in China’s Belt and Road Initiative, and that is paying dividends for science.

Author Correction: Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury

mercredi 15 mai 2019 par Hua-Lin Zhou, Rongli Zhang, Puneet Anand, Colin T. Stomberski, Zhaoxia Qian, Alfred Hausladen, Liwen Wang, Eugene P. Rhee, Samir M. Parikh, S. Ananth Karumanchi, Jonathan S. Stamler
Nature, Published online: 15 May 2019; doi:10.1038/s41586-019-1225-0Author Correction: Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury

A guide to the Nature Index

mercredi 15 mai 2019
Nature, Published online: 15 May 2019; doi:10.1038/d41586-019-01443-9A description of the terminology and methodology used in this supplement, and a guide to the functionality available free online at natureindex.com.

Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy

mercredi 15 mai 2019 par Mauro Di Pilato, Edward Y. Kim, Bruno L. Cadilha, Jasper N. Prüßmann, Mazen N. Nasrallah, Davide Seruggia, Shariq M. Usmani, Sandra Misale, Valentina Zappulli, Esteban Carrizosa, Vinidhra Mani, Matteo Ligorio, Ross D. Warner, Benjamin D. Medoff, Francesco Marangoni, Alexandra-Chloe Villani, Thorsten R. Mempel
Nature, Published online: 15 May 2019; doi:10.1038/s41586-019-1215-2Disruption of the CARMA1–BCL10–MALT1 (CBM) signalosome causes Treg cells to produce IFNγ and develop dominant anti-tumour activity in synergy with anti-PD-1 treatment, and in the absence of (...)

Tracing the origin of adult intestinal stem cells

mercredi 15 mai 2019 par Jordi Guiu, Edouard Hannezo, Shiro Yui, Samuel Demharter, Svetlana Ulyanchenko, Martti Maimets, Anne Jørgensen, Signe Perlman, Lene Lundvall, Linn Salto Mamsen, Agnete Larsen, Rasmus H. Olesen, Claus Yding Andersen, Lea Langhoff Thuesen, Kristine Juul Hare, Tune H. Pers, Konstantin Khodosevich, Benjamin D. Simons, Kim B. Jensen
Nature, Published online: 15 May 2019; doi:10.1038/s41586-019-1212-5Lineage tracing, biophysical modelling and intestinal transplantation approaches are used to demonstrate that, in the mouse fetal intestinal epithelium, cells are highly plastic with respect to cellular identity and, (...)

Ways to give an effective seminar about your research project

mercredi 15 mai 2019 par Ananya Sen
Nature, Published online: 15 May 2019; doi:10.1038/d41586-019-01574-zGrab your audience’s attention by using slides as a roadmap and focusing on your role as a presenter, recommends Ananya Sen.

An apical hypoxic niche sets the pace of shoot meristem activity

mercredi 15 mai 2019 par Daan A. Weits, Alicja B. Kunkowska, Nicholas C. W. Kamps, Katharina M. S. Portz, Niko K. Packbier, Zoe Nemec Venza, Christophe Gaillochet, Jan U. Lohmann, Ole Pedersen, Joost T. van Dongen, Francesco Licausi
Nature, Published online: 15 May 2019; doi:10.1038/s41586-019-1203-6Hypoxia in the shoot meristem of Arabidopsis links the regulation of metabolic activity to development by inhibiting proteolysis of a substrate of the N-degron pathway, which controls class-III homeodomain-leucine zipper (...)

Springer Nature journals unify their policy to encourage preprint sharing

mercredi 15 mai 2019
Nature, Published online: 15 May 2019; doi:10.1038/d41586-019-01493-zRecognizing the benefits, we move from merely supporting the use of preprint servers to promoting it.

Transcriptional cofactors display specificity for distinct types of core promoters

mercredi 15 mai 2019 par Vanja Haberle, Cosmas D. Arnold, Michaela Pagani, Martina Rath, Katharina Schernhuber, Alexander Stark
Nature, Published online: 15 May 2019; doi:10.1038/s41586-019-1210-7A screen of 23 transcriptional cofactors for their ability to activate 72,000 candidate core promoters in Drosophila melanogaster identified distinct compatibility groups, providing insight into mechanisms that underlie the (...)

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