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Transcription factor dimerization activates the p300 acetyltransferase

lundi 15 octobre 2018 par Esther Ortega, Srinivasan Rengachari, Ziad Ibrahim, Naghmeh Hoghoughi, Jonathan Gaucher, Alex S. Holehouse, Saadi Khochbin, Daniel Panne
Transcription factor dimerization activates the p300 acetyltransferase Transcription factor dimerization activates the p300 acetyltransferase, Published online: 15 October 2018; doi:10.1038/s41586-018-0621-1The activation of the histone acetyltransferase p300 depends on the activation and (...)

A metabolite-derived protein modification integrates glycolysis with KEAP1–NRF2 signalling

lundi 15 octobre 2018 par Michael J. Bollong, Gihoon Lee, John S. Coukos, Hwayoung Yun, Claudio Zambaldo, Jae Won Chang, Emily N. Chin, Insha Ahmad, Arnab K. Chatterjee, Luke L. Lairson, Peter G. Schultz, Raymond E. Moellering
A metabolite-derived protein modification integrates glycolysis with KEAP1–NRF2 signalling A metabolite-derived protein modification integrates glycolysis with KEAP1–NRF2 signalling, Published online: 15 October 2018; doi:10.1038/s41586-018-0622-0Inhibition of the glycolytic enzyme PGK1 using a (...)

A protein functionalization platform based on selective reactions at methionine residues

lundi 15 octobre 2018 par Michael T. Taylor, Jennifer E. Nelson, Marcos G. Suero, Matthew J. Gaunt
A protein functionalization platform based on selective reactions at methionine residues A protein functionalization platform based on selective reactions at methionine residues, Published online: 15 October 2018; doi:10.1038/s41586-018-0608-yThis methionine-selective functionalization strategy (...)

Retool AI to forecast and limit wars

lundi 15 octobre 2018 par Weisi Guo, Kristian Gleditsch, Alan Wilson
Retool AI to forecast and limit wars Retool AI to forecast and limit wars, Published online: 15 October 2018; doi:10.1038/d41586-018-07026-4Using artificial intelligence to predict outbursts of violence and probe their causes could save lives, argue Weisi Guo, Kristian Gleditsch and Alan (...)

Astronomy is losing women three times faster than men

lundi 15 octobre 2018 par Mark Zastrow
Astronomy is losing women three times faster than men Astronomy is losing women three times faster than men, Published online: 15 October 2018; doi:10.1038/d41586-018-07018-4Analysis of recruitment data strongly supports anecdotal evidence that the field struggles to retain women early in their (...)

Riskiest landing of Japan's asteroid mission delayed until January

lundi 15 octobre 2018 par Davide Castelvecchi
Riskiest landing of Japan's asteroid mission delayed until January Riskiest landing of Japan's asteroid mission delayed until January, Published online: 15 October 2018; doi:10.1038/d41586-018-07055-zTouchdown of Hayabusa2 mothership has been postponed because of unexpectedly rough (...)

All systems go for second-ever mission to enter Mercury’s orbit

lundi 15 octobre 2018 par Davide Castelvecchi
All systems go for second-ever mission to enter Mercury’s orbit All systems go for second-ever mission to enter Mercury’s orbit , Published online: 15 October 2018; doi:10.1038/d41586-018-06996-9European and Japanese €1.6-billion double probe, BepiColombo, will take seven years to reach the Solar (...)

Daily briefing: “I'm not denying climate change,” says Trump

lundi 15 octobre 2018 par Flora Graham
Daily briefing: “I'm not denying climate change,” says Trump Daily briefing: “I'm not denying climate change,” says Trump, Published online: 15 October 2018; doi:10.1038/d41586-018-07065-x“But I don't know that it's man made,” says the US President. Plus, delve into Stephen Hawking’s final paper (...)

De nouvelles batteries pour les nanosatellites

dimanche 14 octobre 2018 — Espace
CubeSat ASTERIA. ©Wikimedia/NASA's Jet Propulsion LaboratoryUne nouvelle solution pour alimenter les nanosatellites en énergie améliore leur fiabilité et leur efficacité à moindre coût Entre...

Implants dentaires et vapotage font mauvais ménage

dimanche 14 octobre 2018 — Vie et Terre
La fumée de cigarette électronique semble nuire au contact entre les cellules responsables de la formation de tissu osseux et les implants. De plus, elle entraverait la formation de ciment par ces...

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