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Science in Europe: by the numbers

mercredi 22 mai 2019 par Richard Van Noorden, Declan Butler
Nature, Published online: 22 May 2019; doi:10.1038/d41586-019-01565-0The region already hosts some of the world’s leading scientific countries, and some of its smaller states are quickly catching up.

What Europe is getting right about research

mercredi 22 mai 2019
Nature, Published online: 22 May 2019; doi:10.1038/d41586-019-01561-4The European Union’s cross-border collaborative programmes offer lessons for the rest of the world.

Genomic characterization of metastatic breast cancers

mercredi 22 mai 2019 par François Bertucci, Charlotte K. Y. Ng, Anne Patsouris, Nathalie Droin, Salvatore Piscuoglio, Nadine Carbuccia, Jean Charles Soria, Alicia Tran Dien, Yahia Adnani, Maud Kamal, Séverine Garnier, Guillaume Meurice, Marta Jimenez, Semih Dogan, Benjamin Verret, Max Chaffanet, Thomas Bachelot, Mario Campone, Claudia Lefeuvre, Herve Bonnefoi, Florence Dalenc, Alexandra Jacquet, Maria R. De Filippo, Naveen Babbar, Daniel Birnbaum, Thomas Filleron, Christophe Le Tourneau, Fabrice André
Nature, Published online: 22 May 2019; doi:10.1038/s41586-019-1056-zPatient data from six clinical trials are used to compare the genomic landscapes of breast cancer metastases with those of primary tumours, revealing an increase in mutational burden and clonal (...)

Increase in CFC-11 emissions from eastern China based on atmospheric observations

mercredi 22 mai 2019 par M. Rigby, S. Park, T. Saito, L. M. Western, A. L. Redington, X. Fang, S. Henne, A. J. Manning, R. G. Prinn, G. S. Dutton, P. J. Fraser, A. L. Ganesan, B. D. Hall, C. M. Harth, J. Kim, K.-R. Kim, P. B. Krummel, T. Lee, S. Li, Q. Liang, M. F. Lunt, S. A. Montzka, J. Mühle, S. O’Doherty, M.-K. Park, S. Reimann, P. K. Salameh, P. Simmonds, R. L. Tunnicliffe, R. F. Weiss, Y. Yokouchi, D. Young
Nature, Published online: 22 May 2019; doi:10.1038/s41586-019-1193-4Emissions from eastern China account for approximately 40 to 60 per cent of the global rise in emissions of trichlorofluoromethane (CFC-11), which may be a result of new production and (...)

How European scientists will spend €100 billion

mercredi 22 mai 2019 par Alison Abbott, Quirin Schiermeier
Nature, Published online: 22 May 2019; doi:10.1038/d41586-019-01566-zThe European Union has partially approved the shape of its next giant research-spending programme, but it faces political tensions.

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

mercredi 22 mai 2019 par Jason Flannick, Josep M. Mercader, Christian Fuchsberger, Miriam S. Udler, Anubha Mahajan, Jennifer Wessel, Tanya M. Teslovich, Lizz Caulkins, Ryan Koesterer, Francisco Barajas-Olmos, Thomas W. Blackwell, Eric Boerwinkle, Jennifer A. Brody, Federico Centeno-Cruz, Ling Chen, Siying Chen, Cecilia Contreras-Cubas, Emilio Córdova, Adolfo Correa, Maria Cortes, Ralph A. DeFronzo, Lawrence Dolan, Kimberly L. Drews, Amanda Elliott, James S. Floyd, Stacey Gabriel, Maria Eugenia Garay-Sevilla, Humberto García-Ortiz, Myron Gross, Sohee Han, Nancy L. Heard-Costa, Anne U. Jackson, Marit E. Jørgensen, Hyun Min Kang, Megan Kelsey, Bong-Jo Kim, Heikki A. Koistinen, Johanna Kuusisto, Joseph B. Leader, Allan Linneberg, Ching-Ti Liu, Jianjun Liu, Valeriya Lyssenko, Alisa K. Manning, Anthony Marcketta, Juan Manuel Malacara-Hernandez, Angélica Martínez-Hernández, Karen Matsuo, Elizabeth Mayer-Davis, Elvia Mendoza-Caamal, Karen L. Mohlke, Alanna C. Morrison, Anne Ndungu, Maggie C. Y. Ng, Colm O’Dushlaine, Anthony J. Payne, Catherine Pihoker, Wendy S. Post, Michael Preuss, Bruce M. Psaty, Ramachandran S. Vasan, N. William Rayner, Alexander P. Reiner, Cristina Revilla-Monsalve, Neil R. Robertson, Nicola Santoro, Claudia Schurmann, Wing Yee So, Xavier Soberón, Heather M. Stringham, Tim M. Strom, Claudia H. T. Tam, Farook Thameem, Brian Tomlinson, Jason M. Torres, Russell P. Tracy, Rob M. van Dam, Marijana Vujkovic, Shuai Wang, Ryan P. Welch, Daniel R. Witte, Tien-Yin Wong, Gil Atzmon, Nir Barzilai, John Blangero, Lori L. Bonnycastle, Donald W. Bowden, John C. Chambers, Edmund Chan, Ching-Yu Cheng, Yoon Shin Cho, Francis S. Collins, Paul S. de Vries, Ravindranath Duggirala, Benjamin Glaser, Clicerio Gonzalez, Ma Elena Gonzalez, Leif Groop, Jaspal Singh Kooner, Soo Heon Kwak, Markku Laakso, Donna M. Lehman, Peter Nilsson, Timothy D. Spector, E. Shyong Tai, Tiinamaija Tuomi, Jaakko Tuomilehto, James G. Wilson, Carlos A. Aguilar-Salinas, Erwin Bottinger, Brian Burke, David J. Carey, Juliana C. N. Chan, Josée Dupuis, Philippe Frossard, Susan R. Heckbert, Mi Yeong Hwang, Young Jin Kim, H. Lester Kirchner, Jong-Young Lee, Juyoung Lee, Ruth J. F. Loos, Ronald C. W. Ma, Andrew D. Morris, Christopher J. O’Donnell, Colin N. A. Palmer, James Pankow, Kyong Soo Park, Asif Rasheed, Danish Saleheen, Xueling Sim, Kerrin S. Small, Yik Ying Teo, Christopher Haiman, Craig L. Hanis, Brian E. Henderson, Lorena Orozco, Teresa Tusié-Luna, Frederick E. Dewey, Aris Baras, Christian Gieger, Thomas Meitinger, Konstantin Strauch, Leslie Lange, Niels Grarup, Torben Hansen, Oluf Pedersen, Philip Zeitler, Dana Dabelea, Goncalo Abecasis, Graeme I. Bell, Nancy J. Cox, Mark Seielstad, Rob Sladek, James B. Meigs, Steve S. Rich, Jerome I. Rotter, David Altshuler, Noël P. Burtt, Laura J. Scott, Andrew P. Morris, Jose C. Florez, Mark I. McCarthy, Michael Boehnke
Nature, Published online: 22 May 2019; doi:10.1038/s41586-019-1231-2Exome-sequencing analyses of a large cohort of patients with type 2 diabetes and control individuals without diabetes from five ancestries are used to identify gene-level associations of rare variants that are associated with (...)

It’s all my fault, or the Beanstalk sucks

mercredi 22 mai 2019 par Ian Randal Strock
Nature, Published online: 22 May 2019; doi:10.1038/d41586-019-01508-9Scope for improvement.

Europe’s controversial plans to expand defence research

mercredi 22 mai 2019 par Elizabeth Gibney
Nature, Published online: 22 May 2019; doi:10.1038/d41586-019-01567-ySmart drones and artificial intelligence are part of the European Union’s plans for defensive research, but many academics oppose the programme.

Publisher Correction: Sensory experience remodels genome architecture in neural circuit to drive motor learning

mercredi 22 mai 2019 par Tomoko Yamada, Yue Yang, Pamela Valnegri, Ivan Juric, Armen Abnousi, Kelly H. Markwalter, Arden N. Guthrie, Abigail Godec, Anna Oldenborg, Ming Hu, Timothy E. Holy, Azad Bonni
Nature, Published online: 22 May 2019; doi:10.1038/s41586-019-1268-2Publisher Correction: Sensory experience remodels genome architecture in neural circuit to drive motor learning

Publisher Correction: Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis

mercredi 22 mai 2019 par Xing Zeng, Mengchen Ye, Jon M. Resch, Mark P. Jedrychowski, Bo Hu, Bradford B. Lowell, David D. Ginty, Bruce M. Spiegelman
Nature, Published online: 22 May 2019; doi:10.1038/s41586-019-1267-3Publisher Correction: Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis

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